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    Ursolic acid ameliorates cerebral ischemia-reperfusion injury by inhibiting NF-κB/NLRP3-mediated microglia pyroptosis and neuroinflammation

    Ursolic acid ameliorates cerebral ischemia-reperfusion injury by inhibiting NF-κB/NLRP3-mediated microglia pyroptosis and neuroinflammation by Junbin Liu, Junbin Liu, Junbin Liu, Xiaoting Zhang, Xiaoting Zhang, Xiaoting Zhang, Jingpei Guo, Jingpei Guo, Jingpei Guo, Yun Zhang, Yun Zhang, Yun Zhang, Jinming Fan, Jinming Fan, Jinming Fan, Junfeng Liu, Jiawen Chen, Jiawen Chen, Jiawen Chen, Jiawei Jiang, Benshuai Yu, Benshuai Yu, Ke Zhang, Ke Zhang, Ke Zhang, Bin Zhou, Bin Zhou

    Published 2025-07-01

    IntroductionNeuroinflammation is a pivotal factor in the pathophysiology process of ischemic stroke. Undue inflammatory responses are the main cause of neuronal death and infarct enlargement after reperfusion, but there is currently no effective clinical treatment method. Pyroptosis plays an importa...

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