Search Results - Jing Qu

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  1. 1

    Effect of Heat Treatment Time on the Microstructure and Hardness of Particle ReinforcedNi - Base Alloy for Internal Combustion Engine under 1 000 ℃ by CHEN Xiao-jing, QU Jian-hua, DONG Bin

    Published 2021-08-01

    In order to improve the microstructure and properties of nickel-based alloy for internal combustion engine, with selecting nickel-based powder alloy as the test material, the bars with compact microstructure were obtained by hot extrusion consolidation molding method firstly, and then the bars were...

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  2. 2

    Gene therapy strategies for aging intervention by Yaobin Jing, Jie Ren, Jing Qu, Guang-Hui Liu

    Published 2025-08-01

    Aging is characterized by a progressive decline in organ and tissue structure and function, significantly increasing the risk of many chronic diseases. Developing interventions to delay aging holds the potential to reduce the burden of age-associated diseases and promote healthy longevity. Gene ther...

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  3. 3

    PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype by Shunlei Duan, Guohong Yuan, Xiaomeng Liu, Ruotong Ren, Jingyi Li, Weizhou Zhang, Jun Wu, Xiuling Xu, Lina Fu, Ying Li, Jiping Yang, Weiqi Zhang, Ruijun Bai, Fei Yi, Keiichiro Suzuki, Hua Gao, Concepcion Rodriguez Esteban, Chuanbao Zhang, Juan Carlos Izpisua Belmonte, Zhiguo Chen, Xiaomin Wang, Tao Jiang, Jing Qu, Fuchou Tang, Guang-Hui Liu

    Published 2015-12-01

    Abstract PTEN is a tumour suppressor frequently mutated in many types of cancers. Here we show that targeted disruption of PTEN leads to neoplastic transformation of human neural stem cells (NSCs), but not mesenchymal stem cells. PTEN-deficient NSCs display neoplasm-associated metabolic and gene exp...

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