Søgeresultater - Jing LENG
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Review on toxic effects and mechanisms of rare earth neodymium
Udgivet 2025-06-01Få fuldtekstNeodymium, one of the important rare earth elements, is widely used in various fields such as industry, agriculture, and medicine. Neodymium and its compounds can accumulate in the human body through exposure to air, soil, food and so on, leading to various toxic effects. However, research on the to...
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CircRNA_1156 Attenuates Neodymium Nitrate-Induced Hepatocyte Ferroptosis by Inhibiting the ACSL4/PKCβII Signaling Pathway
Udgivet 2025-06-01Få fuldtekstFerroptosis, a form of regulated cell death driven by lipid peroxidation, has been implicated in the pathogenesis of liver diseases. This study investigates the role of circRNA_1156 in neodymium nitrate (Nd(NO<sub>3</sub>)<sub>3</sub>)-induced hepatocyte ferroptosis. Our in v...
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RNA-Seq Analysis of Mouse Hepatocytes AML12 Exposed to Neodymium Nitrate
Udgivet 2025-07-01Få fuldtekstObjective: Neodymium nitrate (Nd(NO<sub>3</sub>)<sub>3</sub>) is widely used globally, raising concerns about its occupational and environmental safety. It enters the human body via the digestive system, accumulates in organs, and causes toxicity, including potential hepatoto...
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<i>Chlorella pyrenoidosa</i> Polysaccharide CPP-3a Promotes M1 Polarization of Macrophages via TLR4/2-MyD88-NF-κB/p38 MAPK Signaling Pathways
Udgivet 2025-07-01Få fuldtekstThe immunomodulatory polysaccharide CPP-3a, purified from <i>Chlorella pyrenoidosa</i>, was investigated for its effects on RAW264.7 macrophages and underlying mechanisms, revealing that CPP-3a significantly enhanced phagocytic capacity and nitric oxide production while upregulating pro-...
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Ruminal microbiome–host metabolome crosstalk in the synthesis of unsaturated fatty acids in buffalo milk
Udgivet 2025-08-01Få fuldtekstABSTRACT: Interactions between rumen microorganisms and their metabolites contribute to milk yield and milk fat content in dairy cows. However, whether rumen microbes and host metabolism affect fatty acid synthesis in milk is unknown. In this study, we investigated the potential regulatory mechanism...
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Screening and characterization of a novel ruminal cellulase gene (Umcel-1) from a metagenomic library of gayal (Bos frontalis)
Udgivet 2016-04-01Få fuldtekstGayal is a rare semi-wild bovine species found in the Indo-China. They can graze grasses, including bamboo leaves, as well as reeds and other plant species, and grow to higher mature live weights than Yunnan Yellow cattle maintained in similar harsh environments. The aim of this study was to identif...
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