Результаты поиска - Jie Cheng

Land surface temperature (LST) is an important parameter in the surface system with drastic variation in spatial and temporal domains. The protection of the ecological environment in mountainous areas and the monitoring of natural disasters require the support of surface temperature data with high s...

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<p>The carbon dioxide (CO₂), which is an environmental friendly working fluid, has good thermal physical properties under the supercritical condition. The heat transfer mechanism and the enhanced heat transfer method of the supercritical CO₂ Brayto...

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Prebiotic oligosaccharides have attracted significant interest in dermatology and skin health due to their ability to modulate the skin microbiome and microbiota–host interactions. This review offers a novel dual perspective, systematically examining the benefits of both oral intake and topical appl...

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Recently, the combination of transarterial intervention therapy (transcatheter arterial chemoembolization [TACE] or hepatic arterial infusion chemotherapy [HAIC]) and systemic therapy for unresectable hepatocellular carcinoma (HCC) has yielded controversial results. In this study, we aimed to evalua...

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This paper focuses on optimizing the management of delayed trains in operational scenarios by scientifically categorizing train delay levels. It employs static and dynamic models grounded in real-world train delay data from high-speed railways. This classification aids dispatchers in swiftly identif...

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The anti-Müllerian hormone (<i>amh</i>) and its receptor, <i>amhr2</i>, along with the downstream bone morphogenetic protein receptors (<i>bmpr</i>s), have been recognized as the central regulators in teleost sex determination (SD) and differentiation. However, th...

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ObjectiveWe aimed to investigate prognostic indicators for pediatric macrolides-unresponsive Mycoplasma pneumoniae pneumonia (MUMPP) cases with A2063/2064G mutations with azithromycin therapy.MethodsThis was a retrospective observational cohort study conducted at the Children’s Hospital of Chongqing...

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<b>Background:</b> Red cell distribution width (RDW) has emerged as a prognostic biomarker in various clinical contexts. This retrospective study evaluated the predictive utility of RDW for cardiopulmonary bypass-associated acute lung injury (CPB-ALI) in pediatric patients undergoing car...

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BackgroundIntervertebral disc degeneration (IVDD) is a major global cause of disability, and mesenchymal stem cell (MSC) therapy offers a promising regenerative solution by targeting the root causes of degeneration, unlike conventional symptom-focused treatments. This bibliometric analysis explores...

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Acetaminophen (APAP) overdose is the leading cause of acute liver failure and a major global health issue. APAP hepatotoxicity is primarily driven by oxidative stress resulting from the depletion of hepatic glutathione (GSH). Given that hydrogen sulfide (H2S) and albumin are crucial components of th...

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Eukaryotic genomes are hierarchically packaged into cell nucleus, affecting gene regulation. The genome is organized into multiscale structural units, including chromosome territories, compartments, topologically associating domains (TADs), and DNA loops. The identification of these hierarchical str...

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Oral squamous cell carcinoma (OSCC), an aggressive and poorly prognosed subtype of head and neck squamous cell carcinoma (HNSCC), has prompted urgent calls for innovative therapeutic approaches. Evodiamine (EVO), a natural alkaloid extracted from the Chinese herb <i>Evodia rutaecarpa</i>...

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BackgroundEndometriosis is a common disease among women of childbearing age. However, the molecular mechanism behind it is still unknown. Therefore, new biomarkers and therapeutic targets are needed to improve the diagnosis and treatment of infertile women.MethodsMicroarray datasets GSE7305, GSE7307...

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卒中是全球致死致残的首要病因。基于人工智能（artificial intelligence，AI）融合临床与多组学数据的研究范式，为卒中精准防治提供了新方案。AI技术通过整合分析临床与多组学数据，能够提升卒中高危人群识别能力，优化早期诊断与风险评估，实现卒中亚型的精准分型，同时可筛选潜在药物靶点，构建预后预测模型。然而，卒中多组学资源相对匮乏、多模态数据融合困难，以及算法可解释性不足等仍是临床转化的主要瓶颈。本文对AI融合临床与多组学数据在卒中防治及医药研发中的应用与挑战等研究进展进行综述。Abstract: Stroke is the leading global cause of dea...

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ObjectivesTo evaluate the therapeutic efficacy of different doses of tocilizumab (TCZ) in patients with severe or critical COVID–19.MethodsIn this single–center retrospective cohort study conducted from January 2023 to January 2024, 56 hospitalized patients with severe or critical COVID–19 who recei...

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Gelatin hydrolysates have been extensively used as nutraceutical agents, exhibiting significant biological activity. This study aimed to compare the antioxidant activity and enhancement of collagen expression in human skin fibroblast (HDF-α) cells treated with gelatin hydrolysates from different sou...

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