Search Results - Jiayi Huang

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  1. 1
    The role of BMAL1 in glial cells: Implications for cognitive function in neurodegenerative diseases

    The role of BMAL1 in glial cells: Implications for cognitive function in neurodegenerative diseases by Zhimin Ding, Yueyang Zhuang, Jiawei Jian, Tao Jiang, Jiayi Huang, Minguang Yang, Lei Yang, Weilin Liu

    Published 2025-09-01

    Disruption of the circadian rhythm may precede the typical clinical symptoms of neurodegenerative diseases and is a potential risk factor for Alzheimer’s disease (AD), associated dementias, and Parkinson’s disease (PD). The morphology and function of mammalian glial cells and their gene expression c...

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  2. 2
    Genetic testing and Guangdong college students in China: A cross-sectional study of knowledge and attitudes

    Genetic testing and Guangdong college students in China: A cross-sectional study of knowledge and attitudes by Jiaming Wang, Ruoru Lin, Sijing Luo, Beilei Zhong, Yuran Zhu, Jiayi Huang, Dangui Zhang, William Ba-Thein

    Published 2025-08-01

    Objective: This study investigated functional health literacy and attitudes toward genetic testing among Chinese college students to understand if they can make informed decisions and avoid potential risks. Methods: A cross-sectional anonymous online survey was conducted with students from 13 colleg...

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  3. 3
    Effects of 1-Methylcyclopropene Combined with Konjac Glucomannan/κ-Carrageenan Coating Treatment on the Quality of Pears during Shelf Life

    Effects of 1-Methylcyclopropene Combined with Konjac Glucomannan/κ-Carrageenan Coating Treatment on the Quality of Pears during Shelf Life by ZHANG Yi, WANG Jiayi, HUANG Wen, ZHANG Yingtong, LING Jun, LI Pengxia, CHENG Shunchang, YANG Qingsong, ZHOU Hongsheng

    Published 2025-05-01

    In order to study the effect of 1-methylcyclopropene (1-MCP) combined with konjac glucomannan/κ-carrageenan (KGM/KC) coating treatment on the preservation of pears, ‘Sucui 1’ pears subjected to one of four treatments: water (control), 1-MCP, KGM/KC coating, and 1-MCP + KGM/KC coating was evaluated f...

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  4. 4
    Aloe-emodin mediates the inhibitory effect of LncRNA D63785 on the PI3K/Akt/mTOR pathway in nasopharyngeal carcinoma

    Aloe-emodin mediates the inhibitory effect of LncRNA D63785 on the PI3K/Akt/mTOR pathway in nasopharyngeal carcinoma by Min He, Lei Xie, Lei Xie, Jiayi Huang, Han Su, Jiahua Hu, Liuping Xie, Liuping Xie, Mengqin Li, Mengqin Li, Xin Zeng, Xin Zeng, Jianhong Tang, Jianhong Tang, Jianhong Tang

    Published 2025-07-01

    BackgroundLong non-coding RNAs (lncRNAs) are dysregulated in nasopharyngeal carcinoma (NPC), yet their interplay with pharmacological agents like aloe-emodin (AE) remains unclear. This study explores AE’s anti-NPC mechanisms via lncRNA D63785 and the PI3K/Akt/mTOR pathway.MethodsNPC cells (CNE1, C66...

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  5. 5
    Translocation of SIRT6 promotes glycolysis reprogramming to exacerbate diabetic angiopathy

    Translocation of SIRT6 promotes glycolysis reprogramming to exacerbate diabetic angiopathy by Kemiao Pang, Jiayi Huang, Shiwu Zhang, Yinghui Guan, Ning Zou, Jiaxin Kang, Haining Du, Dechao Zhao, Denis V. Abramochkin, Heyu Chen, Nan Zhang, Yunyan Gu, Ning Liu, Yining Niu, Ziqi Xiong, Xueya Zhang, Fanghao Lu, Huitao Fan, Jinwei Tian, Bo Yu, Shuijie Li, Weihua Zhang

    Published 2025-09-01

    Diabetic angiopathy, a major complication of type 2 diabetes mellitus (T2DM), is driven by vascular dysfunction, metabolic reprogramming, and oxidative stress. NAD+-dependent deacetylase SIRT6, located in the nucleus, is recognized for its role in modulating cardiovascular and metabolic homeostasis...

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