Search Results - Jiaqiang Zhang
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Mercury Deposition in South China Across the Ordovician‐Silurian Transition: Implications for Climate Change
Published 2025-07-01Get full textAbstract Most of the global climate changes are closely associated with volcanic activity. However, the link between global cooling during the Ordovician‐Silurian (O‐S) transition and volcanism remains unclear due to limited constraints on large volcanic events before, during, and after the peak of...
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Development and validation of a risk prediction model for perioperative acute kidney injury in non-cardiac and non-urological surgery patients: a retrospective cohort study
Published 2025-07-01Get full textBackgroundThis study presents a predictive model designed to fill the gap in tools for predicting perioperative acute kidney injury (AKI) in patients undergoing non-cardiac, non-urological surgeries, with the goal of improving clinical decision-making and patient outcomes.MethodsA retrospective coho...
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Development and validation of an interpretable risk prediction model for perioperative ischemic stroke in noncardiac, nonvascular, and nonneurosurgical patients: a retrospective st...
Published 2025-07-01Get full textBackgroundPerioperative stroke is a severe complication for patients undergoing non-cardiac, non-vascular, and non-neurosurgical surgeries, resulting in significant morbidity and mortality. Despite its clinical relevance, effective predictive models for stroke risk in this population are scarce. Thi...
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Impact of perioperative dexmedetomidine on recurrence and survival outcomes in oral cavity squamous cell carcinoma
Published 2025-07-01Get full textObjectives To investigate the association between perioperative dexmedetomidine (DEX) use and oncological outcomes—including locoregional recurrence (LRR) and distant metastasis (DM)—in patients undergoing curative surgery for oral cavity squamous cell carcinoma (OCSCC).Methods This retrospective co...
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3D genome organization and its study in livestock breeding
Published 2024-01-01Get full textEukaryotic genomes are hierarchically packaged into cell nucleus, affecting gene regulation. The genome is organized into multiscale structural units, including chromosome territories, compartments, topologically associating domains (TADs), and DNA loops. The identification of these hierarchical str...
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Evaluating GLP-1 receptor agonists versus metformin as first-line therapy for reducing dementia risk in type 2 diabetes
Published 2025-07-01Get full textIntroduction No direct comparisons have evaluated glucagon-like peptide-1 receptor agonists (GLP-1 RAs) versus metformin as first-line antidiabetic therapy for preventing dementia in patients with type 2 diabetes mellitus (T2DM). This study aimed to assess the comparative effectiveness of GLP-1 RAs...
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Capnography monitoring reduces the incidence of hypoxia in older patients undergoing gastrointestinal endoscopy under propofol sedation
Get full textBackground and aims: Whether routine capnography monitoring during gastrointestinal endoscopy sedation can reduce the occurrence of hypoxia is controversial. Older patients are more prone to hypoxia. This study aimed to determine the effect of additional capnography monitoring on the incidence of hy...
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Efficacy and safety of peripherally-restricted κ-opioid receptor agonist-HSK21542 for postoperative analgesia in patients undergoing laparoscopic abdominal surgery: a randomized, p...
Published 2025-07-01Get full textBackgroundThis phase 2 trial comprised dose exploration (stage 1) and dose confirmation stages (stage 2) to determine the safety and efficacy of HSK21542 in patients undergoing laparoscopic abdominal surgery.MethodsIn stage 1, patients were randomly allocated at a ratio of 4:1 (12 to receive HSK2154...
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Efficacy of a nasal mask oxygen kit versus regular nasal cannula in sedated gastrointestinal endoscopy: a multicentre, randomised clinical trial
Published 2025-07-01Get full textObjective The incidence of hypoxia in painless gastrointestinal endoscopy is not negligible. A nasal mask oxygen kit may reduce the incidence of hypoxia compared with a regular nasal cannula.Methods This multi-centre, randomised, open-label clinical trial took place from 1 September 2022 to 6 June 2...
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