Search Results - Jian Zhou

Jian Zhou

Jian Zhou (; February 24, 1957 – March 9, 1999) was a Chinese virologist and cancer researcher, who with fellow researcher Ian Frazer, invented Gardasil and Cervarix, the vaccines for stimulating human immunological resistance to the cervical cancer-inducing human papilloma virus. Provided by Wikipedia
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  1. 1

    Predicting the minimum horizontal principal stress using genetic expression programming and borehole breakout data by Rui Zhang, Jian Zhou

    Published 2025-07-01

    As a critical component of the in situ stress state, determination of the minimum horizontal principal stress plays a significant role in both geotechnical and petroleum engineering. To this end, a gene expression programming (GEP) algorithm-based model, in which the data of borehole breakout size,...

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  2. 2

    An open access 90 m resolution VS data and map for areas affected by the January 2025 M6.8 Dingri Xizang, China earthquakeKey points by Jian Zhou, Li Li

    Published 2025-08-01

    In this study, we developed a high-resolution (3 arcsec, approximately 90 m) VS map and associated open-access dataset for the 140 km × 200 km region affected by the January 2025 M6.8 Dingri Xizang, China earthquake. This map provides a significantly finer resolution compared to existing VS maps, wh...

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  3. 3

    The Principle and Application of Achromatic Metalens by Runsheng Liu, Lihua Li, Jian Zhou

    Published 2025-05-01

    Metalenses, as ultrathin planar optical devices based on metasurfaces, have attracted significant research interest in recent years due to their compact structure and versatile light manipulation, showing great potential to replace traditional lenses in specific applications. This review focuses on...

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  4. 4

    A Hierarchically Structured Ni-NOF@ZIF-L Heterojunction Using Van Der Waals Interactions for Electrocatalytic Reduction of CO<sub>2</sub> to HCOOH by Liqun Wu, Xiaojun He, Jian Zhou

    Published 2025-07-01

    The electrocatalytic CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR) offers an energy-saving and environmentally friendly approach to producing hydrocarbon fuels. The use of a gas diffusion electrode (GDE) flow cell has generally improved the rate of CO<sub>2</s...

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  5. 5

    Development of the Optuna-NGBoost-SHAP model for estimating ground settlement during tunnel excavation by Yuxin Chen, Mohammad Hossein Kadkhodaei, Jian Zhou

    Published 2025-10-01

    This study aims to develop and evaluate a natural gradient boosting (NGBoost) model optimized with Optuna for estimating ground settlement during tunnel excavation, incorporating Shapley additive explanations (SHAP) to perform interpretability analysis on the model’s estimation results. The model’s...

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  6. 6

    Signal Processing Method and Evaluation Method for Weak Doppler Signal Detection by Chongbin Xi, Jian Zhou, Xiaoming Nie, Shilong Jin

    Published 2025-06-01

    When the amplitude of the laser Doppler signal is less than that of the noise amplitude, the speed information cannot be identified. In this paper, the recognition of weak Doppler signals is accomplished by superimposing multiple-frame Doppler signals in the frequency domain and eliminating the base...

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  7. 7

    Protein arginine N-methyltransferase 1 promotes the proliferation and metastasis of hepatocellular carcinoma cells by Qing Gou, ShuJiao He, ZeJian Zhou

    Published 2017-02-01

    Hepatocellular carcinoma is the most common subtype of liver cancer. Protein arginine N-methyltransferase 1 was shown to be upregulated in various cancers. However, the role of protein arginine N-methyltransferase 1 in hepatocellular carcinoma progression remains incompletely understood. We investig...

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  8. 8

    Pulse width compression technology of high-energy laser for Thomson scattering diagnostics by Jian Zhou, Shumei Xiao, Qing Zang, Wen Chu

    Published 2025-06-01

    The laser beam with a narrow pulse width enhances the signal-to-noise ratio of the Thomson scattering system. A laser system’s chopping module has been designed to compress the pulse width to improve the peak power. The chopping module is positioned between the oscillator and the first amplification...

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  9. 9

    Ferroptosis in central nervous system injuries: molecular mechanisms, diagnostic approaches, and therapeutic strategies by Qiuhu Huang, Haowen Zhang, Shenbo Chen, Yao Wang, Jian Zhou

    Published 2025-07-01

    Ferroptosis, an iron-dependent form of cell death, has emerged as a critical factor in the pathogenesis of central nervous system (CNS) injuries, including neurodegenerative diseases, stroke, and traumatic brain injury. This review highlights disrupted iron metabolism, glutathione depletion, and ant...

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  10. 10

    Large-Dynamic-Range Dual-Parameter Sensor Using Broad FSR Multimode Photonic Crystal Nanobeam Cavity by Chao Wang, Zhongyuan Fu, Fujun Sun, Jian Zhou, Huiping Tian

    Published 2018-01-01

    We theoretically propose an ultracompact large-dynamic-range dual-parameter sensor using a broad free spectral range (FSR) multimode photonic crystal nanobeam cavity (MM-PCNC). In the multimode regime, each resonant mode is exploited as an independent sensing channel. Broad FSR (&gt;100 nm) is a...

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  11. 11

    Interpretable Ensemble Learning with Lévy Flight-Enhanced Heuristic Technique for Strength Prediction of MICP-Treated Sands by Yingui Qiu, Shibin Yao, Hongning Qi, Jian Zhou, Manoj Khandelwal

    Published 2025-07-01

    Microbially-induced calcite precipitation (MICP) has emerged as a promising bio-geotechnical technique for sustainable soil improvement, yet accurate prediction of treatment effectiveness remains challenging due to complex multi-factor interactions. This study develops an ensemble learning framework...

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  12. 12

    Vibration Localization in Cyclic Mistuned Structure and Its Application to Low-Frequency Broadband Vibration Control of Pipelines by Lihang Yin, Wei Xu, Jian Zhou, Song Liu, Liantao Xiao

    Published 2025-06-01

    This paper proposes a pipeline vibration control method based on the vibration localization energy dissipation principle of cyclic mistuned structure (CMS). The influence of the frequency mistuning strength and coupling strength of the resonant units on vibration localization characteristics is stud...

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  13. 13

    Development and application of vibrating dynamic culture system for mouse oocytes and embryos by Qinli Liu, Sen Zhao, Jian Zhou, Yu Shi, Chongyang Ye, Bo Huo

    Published 2025-07-01

    BackgroundMammalian oocytes fertilization and early embryos development primarily take place in the fallopian tube, which not only provides nutrients but also offers a suitable mechanical environment. The current culture system for oocytes and embryos in assisted reproductive technology is static, l...

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  14. 14

    Activation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway by Tongbo Yi, Xiaoqing Zhou, Kai Sang, Xuchen Huang, Jian Zhou, Lan Ge

    Published 2019-12-01

    This study aimed to investigate the effect and potential modulation mechanism of lnc-SLC4A1-1 on breast cancer (BC) carcinogenesis. The expression of lnc-SLC4A1-1 in tissue and serum samples from BC patients, as well as BC cell lines, was detected by real-time quantitative reverse transcription-poly...

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  15. 15

    Current status of medical research among undergraduate medical students in China: a nationwide questionnaire survey by Liuyan Xu, Jian Zhou, Chengxi Fan, Kailin Huang, Abudukerimu Muyesha, Rurong Wang, Xuehan Li

    Published 2025-07-01

    The increasing demand for physician-scientists highlights the essential role of medical schools in fostering the development of these professionals. This study aims to assess the current status of research engagement, attitudes toward research, and barriers to participation among Chinese undergradua...

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  16. 16

    A cutting-edge atomization-based methodology for enhancing formulation ability to resist photoaging by Juntong Li, Shuyu Wang, Ruifang Han, Meifang Wu, Jian Zhou, Peibiao Zhao, Bin Cui

    Published 2024-12-01

    Background: Skin photoaging mainly occurs in exposed skin irradiated by ultraviolet rays from the sunlight. When exposed to ultraviolet rays, the skin will undergo certain changes to avoid damage. The inflammatory factors produced by light stimulation will induce melanocytes to produce more melanin,...

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  17. 17

    The efficacy study of trinity permeation synergism on anti-aging by Ruifang Han, Shuyu Wang, Juntong Li, Meifang Wu, Jian Zhou, Peibiao Zhao, Bin Cui

    Published 2024-09-01

    Background: More and more consumers are paying attention to skin rejuvenation. However, there is a lack of a non-invasive and efficient solution. Objective: To evaluate the efficacy of a trinity permeation synergism (TPS), which consists of a firming essence, an atomizer and a photoelectric penetrat...

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  18. 18

    The role of geriatric nutritional risk index in predicting survival of type B aortic dissection patients after thoracic endovascular aortic repair by Kaiwen Zhao, Jinzhu Niu, Yuzhen He, Lingxu Kong, Wenyao Zhao, Qingsheng Lu, Shuangshuang Li, Jian Zhou

    Published 2025-07-01

    Background: The geriatric nutritional risk index (GNRI) is a reliable indicator of patients’ nutrition status and has been shown to be valuable in predicting the outcome of patients with various cardiovascular diseases. This study explored the association between perioperative GNRI and the prognosis...

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  19. 19

    Whole-genome characterization and antibiotic resistance phenotype of Escherichia marmotae first isolated from Berylmys bowersi by Ying Liu, Jian Zhou, Tao Gu, Weiwei Ai, Jingzhu Zhou, Qing Ma, Yong Hu, Shijun Li

    Published 2025-07-01

    ABSTRACT Escherichia marmotae was first described in 2015 as a bacterium isolated from Himalayan marmots, with recent evidence suggesting its potential to cause human diseases. This study presents the first report of E. marmotae isolation from Berylmys bowersi in Guizhou province. We conducted genet...

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  20. 20

    Biological applications of graphene-based nanomaterials in neurodegenerative diseases by Rong-kun Zhu, Jun Shi, Hong-jian Zhou, Ling Ge, Wen-hao Yin, Hui Zeng, Xiong-wei Wang

    Published 2025-08-01

    Neurodegenerative diseases (NDDs) have become a major challenge in global public health due to neurotoxicity caused by progressive neuronal degeneration and abnormal protein aggregation, which has attracted widespread attention. Graphene-based nanomaterials provide innovative solutions for the early...

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