検索結果 - Jiahui Li

IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by decreased memory and cognitive impairment. Abnormal tau hyperphosphorylation ultimately forms neurofibrillary tangles, which is one of the most important pathological features of AD. Since we have previo...

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Eliminating all forms of poverty is a core component of the United Nations’ Sustainable Development Goals. At the household level, poverty and income inequality significantly threaten farmers’ sustainable development and food security. Based on a sample of 1234 kiwi farmers from the Shaanxi and Sich...

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BackgroundThe decline in muscle mass is a common concern among perimenopausal women. However, the association between menopause-related symptoms and muscle mass remains inconclusive, and the mechanistic role of estrogen is still unclear.MethodsThe study included 407 peri- and postmenopausal women ag...

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To address the widespread challenges of significant multi-category dental morphological variations and interference from overlapping anatomical structures in panoramic dental X-ray images, this paper proposes a dual-stream dental segmentation model based on Transformer heterogeneous feature compleme...

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The integration of artificial intelligence (AI) into education requires frameworks that are not only technically robust but also ethically and pedagogically grounded. This paper proposes the Generalist Education Artificial Intelligence (GEAI) framework—a conceptual blueprint designed to enable priva...

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ObjectivesLip bumpers (LB) treatment has been used to expand the mandibular arch during mixed dentition. The aim of this study is to evaluate the effects of LB on the mandibular transverse changes in the canine and premolar regions using CBCT.Materials and methodsThis retrospective study utilized pr...

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Interfacial reactions and microstructure evolution of Al/Sn-3.5mass%Ag (SA)/Al, Al/Sn-3.0mass%Ag-0.5mass%Cu (SAC305)/Al, and Cu/SA/Al joints were investigated in this study. The microstructure of the intermetallic compound (IMC) was studied at soldering temperature of 250 °C and a thermal aging temp...

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A kinase interacting protein 1 (AKIP1) is a signal transduction junction protein that promotes physiological hypertrophy. This study aimed to investigate whether exercise induces AKIP1 to promote physiological cardiac hypertrophy and the effects for signaling pathways. 24 6-week-old C57BL/6 N male m...

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A novel actinobacterial strain, designated E54^T, was isolated from a hyper-arid desert soil sample collected from the Kumtagh Desert in Dunhuang, Gansu Province, China. Phylogenetic analysis based on 16S rRNA gene sequences placed strain E54^T within the...

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A series of 2-halo-3-formylindole molecules were synthesized via Vilsmeier–Haack haloformylation reaction of N-Boc-oxindole with POCl3 or POBr3 and DMF, which are free from the use of catalyst and solvent. Moreover, through several simple postprocessing steps, corresponding adducts can be readily tr...

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The prevalence of obesity has steadily increased over the past few decades. Previous studies suggest that obesity is an oncogenic factor and that over 20% of all cancers are obesity-related. Among such cancers, digestive system malignancies (including esophageal adenocarcinomas, colorectal cancers,...

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Protein Kinase A (PKA) is found in a wide range of body tissues and is involved in various cellular activities. PKA has been observed to interact with key proteins in the nuclear factor kappa-B (NF-κB) pathway to activate the pathway, thereby triggering an inflammatory response. However, the role of...

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We studied changes in the concentrations of aggregate-cementing agents after different reclamation times and with different fertilization regimes, as well as the formation mechanism of aggregates in reclaimed soil, to provide a theoretical basis for rapid reclamation of soil fertility in the subside...

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BackgroundPrecise assessment of brain aging is crucial for early detection of neurodegenerative disorders and aiding clinical practice. Existing magnetic resonance imaging (MRI)–based methods excel in this task, but they still have room for improvement in capturing local morp...

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