Search Results - Jia Meng
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Secretion of transthyretin: molecular mechanisms dependent on the endoplasmic reticulum
Published 2025-07-01Get full textHereditary transthyretin amyloidosis (ATTRv) results from genetic mutations that destabilize transthyretin (TTR), leading to the formation of extracellular aggregates and amyloid fibrils. A common pathological feature of ATTRv is the capacity of TTR variants to evade endoplasmic reticulum quality co...
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Phylogeography of the Endangered Endemic <i>Perkinsiodendron macgregorii</i> Based on Chloroplast Genome Data
Published 2025-06-01Get full text<i>Perkinsiodendron macgregorii</i>, an endangered Chinese endemic tree with high ornamental and ecological value, faces extinction threats due to its poor natural regeneration and habitat degradation. Despite the urgent need for its conservation, the genetic architecture and population...
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Global, regional, and national time trends in falls and their predictions: an age-period-cohort analysis of the Global Burden of Disease Study 2021
Published 2025-08-01Get full textBackgroundFalls are a global public health issue with a heavy disease and socioeconomic burden, with an increasing number of risky people. The aim of this study is to explore the global disease burden of falls and to provide a scientific basis for the prevention and management of falls.MethodsThis s...
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Characterization of a blaCTX-M-3, blaKPC-2 and blaTEM-1B co-producing IncN plasmid in Escherichia coli of chicken origin
Published 2023-01-01Get full textAn extensively drug-resistant (XDR) Escherichia coli strain 258E was isolated from an anal swab sample of a chicken farm of Anhui Province in China. Genomic analyses indicated that the strain 258E harbors an incompatibility group N (IncN) plasmid pEC258-3, which co-produces blaCTX-M-3, blaKPC-2, bla...
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