Search Results - J M Schwarz

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    Enhanced extracellular matrix remodeling due to embedded spheroid fluidization

    Enhanced extracellular matrix remodeling due to embedded spheroid fluidization by Tao Zhang, Shabeeb Ameen, Sounok Ghosh, Kyungeun Kim, Mrinal Pandey, Brian C H Cheung, Minh Thanh, Alison E Patteson, Mingming Wu, J M Schwarz

    Published 2025-01-01

    Embedding a collective of tumor cells, i.e. a tumor spheroid, in a fibrous environment, such as a collagen network, provides an essential in vitro platform to investigate the biophysical mechanisms of tumor invasion. To predict new mechanisms, we develop a three-dimensional computational model of an...

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