Search Results - Ivan Ivanov
Ivan Ivanov
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A Study on Tumor-Infiltrating Lymphocytes in Different Subtypes of Breast Cancer
Published 2021-06-01Get full textThe study aimed to investigate immune cell infiltration in different subtypes of breast cancer (BC). Retrospectively were selected 100 patients with primary BC, grouped into four molecular surrogate subtypes (Luminal A and Luminal B-like, HER2-positive and triple-negative - TN), determined by immuno...
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Assessment of the Effect of Treatment with Neoadjuvant Chemotherapy on Breast Cancer Axillary Lymph Node
Published 2013-12-01Get full textNeoadjuvant chemotherapy is the standard of care for patients with locally advanced breast cancer (LABS). The aim of this study was to determine the effects of neoadjuvant chemotherapy on metastatic and nonmetastatic breast cancer axillary lymph nodes (ALNs). Seventy-seven patients with LABS and cyt...
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Prevention of Preterm Birth
Published 2014-01-01Get full textPreterm birth (PTB) is a worldwide problem with great social significance because it is a leading cause of perinatal complications and perinatal mortality. PTB is responsible for more than a half of neonatal deaths. The rate of preterm delivery varies between 5-18% worldwide and has not decreased in...
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Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma
Published 2014-11-01Get full textTriple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein. According to DNA microarray profiling, breast cancer was divided into several molecular subgroups, including Luminal A and Luminal B; HER2 overexpressi...
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A Case of “Microinvasive Carcinoma of the Bronchus”
Published 2019-01-01Get full textDeciding on a treatment approach for early stage lung cancer (0-1) is sometimes difficult because of uncertainties regarding the depth of tumour invasion and its margins. Even with advanced technology, such as endobronchial ultrasound and autofluorescence bronchoscopy, it is often difficult to be pr...
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Three-Dimensional Reconstruction of Arterial-Lymphatic Vascular Complex (Vessel Within the Vessel) in Breast Tissue
Published 2013-07-01Get full textThe phenomenon “vessels within vessels” was initially described by Merchant S et al. as arteries found free-floating inside the lumen of veins. We have described another version of the “vessels within vessels”complex, composed of arteries found inside the lumen of lymphatic vessels. The purpose of t...
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Prevalence of Five BRCA1/2 Mutations in Bulgarian Breast Cancer Patients
Published 2019-01-01Get full textDetection of mutations in breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) gene is an effective method of early diagnosis and prevention of breast cancer (BC). The mutational spectrum of both genes in Bulgarian population has not been studied in depth. The aim of this study was to investigate the...
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Study of the Carrier State for Five BRCA1/BRCA2 Deleterious Mutations in Bulgarian Women with Breast Cancer
Published 2013-12-01Get full textGenetic testing for BRCA 1/2 mutation is a well recognized medical management tool. Identification of healthy carriers of such mutations allows effective risk reduction procedures to be performed. There is no data reported on the founder mutations in the Bulgarian population. To evaluate the contrib...
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Statistical Analysis of the Forensic Autopsies, Performed in the Department of Forensic Medicine of University Hospital Pleven for the Period 2009-2013 (A Preliminary Report)
Published 2016-09-01Get full textThe study is a statistical analysis of the dynamics and structure of forensic autopsies performed on dead bodies and body remains at University Hospital “Dr. Georgi Stranski” in Pleven. The study was based on forensic autopsy records database and forensic autopsy reports for the period 2009-2013. A...
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Chamomile Matters: Species- and Producer-Dependent Variation in Bulgarian <i>Matricaria recutita</i> L. and <i>Chamaemelum nobile</i> L. Essential Oils and Their Cosmetic Potential
Published 2025-06-01Get full textChamomile essential oils (EOs) are widely used in cosmetics for their antioxidant, anti-inflammatory, and antimicrobial properties. Bulgaria, with its long-standing tradition in EO production, provides an ideal setting to examine the influence of species and cultivation practices on oil quality. Thi...
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