Search Results - I. Yu. Pirogova

Aim of investigation. To present data on screening investigation of patients at suspicion for diffuse liver disease, including series of routine methods specified by medical standards.Original positions. Article presents data on diagnostic accuracy, sensitivity, specificity of taken into account met...

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Aim of investigation. The standard of diffuse liver disease (DLD) diagnostics, allowing to determine etiology, stage of liver fibrosis (LF), histological activity index (HAI) is the liver biopsy (LB). At inaccessibility of LB for diagnostics, LF stage can be assessed by noninvasive methods based on...

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Aim of the study. To estimate efficacy and safety of cepeginterferon-alpha 2b (cPEG-IFNα2b) and ribavirin combination for the treatment of chronic hepatitis C (CHC), to define necessity of IL-28V genetic polymorphism diagnostics, to estimate liver elastometry scores at the background of antiviral th...

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Aim. This study is aimed at evaluating the efficacy and safety of Bicyclol administration in patients suffering from non-alcoholic fatty liver disease (NAFLD) («ZIGUN» research) by monitoring laboratory data and non-invasive methods of diagnosis of liver fibrosis and steatosis.Materials and methods....

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Aim of investigation. To study potentials of noninvasive methods application for assessment of liver fibrosis at screening diagnosis of patients with diffuse liver diseases.Material and methods. Overall 188 HCV RNApositive patients and 61 HBV DNA-positive were investigated. The stage of disease in a...

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Aim. To evaluate effects of ursodeoxycholic acid (UDCA) on inflammation, steatosis and liver fibrosis and atherogenesis factors in patients with non-alcoholic fatty liver disease (NAFLD).Materials and methods. The study included 139 patients with NAFLD who received 15 mg/kg of UDCA (Ursosan®) per da...

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Aim of investigation. To estimate outcomes of toxic hepatites (TH) after intake of alcohol surrogates («Mozhzhevelovy» spirit for external use) with development of original prognostic model of patients survival.Material and methods. Retrospective analysis of clinical and laboratory data and survival...

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In the Russian Federation, liver diseases are most frequently represented by two their nosological forms, i.e., nonalcoholic and alcoholic fatty liver disease (NAFLD and ALD). A successful management of such patients, along with improving the functional state of the liver, requires a careful analysi...

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Aim of investigation. To study the role of serological markers of hepatitis B virus infection: antibodies to hepatitis B virus cor-antigen (anti-HВcor IgG) in progressing liver damage at patients with persistent hepatitis C virus infection.Material and methods. For the first time in the large group...

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The aim of publication. To present the case of severe acute drug-induced hepatitis after halothane anesthesia in relation to significance of allergies history preoperative inquiry and assessment of medical management of patients, using modern prognostic scales.Key points. Biotransformation of volati...

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Aim. This observational (non-interventional) study was aimed at obtaining data on practitioners’ commitment to prescribing rifaximin-α therapy to patients with uncomplicated diverticular disease (UDD), to assess patients’ adherence to such prescriptions, as well as to assess physicians’ and patients...

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