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Assessment of the allergenic and immunotoxic properties of the recombinant non-immunogenic staphylokinase in preclinical and clinical trials by S. S. Markin, S. V. Ivanov, I. P. Beletsky, M. V. Zakharova, E. A. Ponomarev, E. V. Arzamascev
Published 2025-07-01The aim. To study possible allergenic and immunotoxic properties of the recombinant non-immunogenic staphylokinase molecule with the amino acids replacement Lys74, Glu75 and Arg77 with alanine in preclinical and clinical studies.Materials and methods. The allergenic and immunotoxic properties of the...
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