Search Results - I. I. Zhidkova
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GENOMIC FACTORS (TOLL-LIKE RECEPTORS GENES) IN DEVELOPMENT OF ATHEROSCLEROSIS AND ITS CLINICAL MANIFESTATIONS
Published 2017-07-01Get full textDevelopment of atherosclerosis and its clinical manifestations, i.e. unstable angina, myocardial infarction, and ischemic stroke, is largely determined by a genetic inheritance, particularly inherited variation of the genes encoding Toll-like receptors (TLRs), a major effector of innate immune syste...
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Coagulation status in patients with pulmonary embolism receiving long-term anticoagulant therapy
Published 2022-01-01Get full textAim. To study the blood coagulation status by various laboratory methods in patients after pulmonary embolism (PE) receiving long-term anticoagulant therapy.Material and methods. The blood of 23 patients with pulmonary embolism, who received long-term anticoagulant therapy, was studied. The study of...
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ROLE OF CARDIAC-ANKLE VASCULAR INDEX IN PREDICTION OF LONG TERM ADVERSE OUTCOMES IN PATIENTS WITH NON ST ELEVATION ACUTE CORONARY SYNDROME
Published 2018-02-01Get full textAim. Evaluation of the association of cardiac-ankle vascular index and development of adverse outcomes in patients after non-ST elevation acute coronary syndrome (NSTEACS).Material and methods. To the registry of NSTEACS in 2009. Totally, 415 patients had been included. The group of main long term (...
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The impact of comorbidities and age on the nosocomial outcomes of patients undergoing coronary artery bypass grafting
Published 2019-04-01Get full textAim. To assess the incidence of unfavorable in-hospital outcomes (fatal and non-fatal complications) following coronary artery bypass grafting (CABG), depending on the age of the patient and the presence of comorbidities.Material and methods. In the period from 2011 to 2012 we included in the study...
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THE ROLE OF TOLL-LIKE RECEPTORS POLYMORPHISM IN ATHEROSCLEROSIS COMPLICATIONS DEVELOPMENT
Published 2015-12-01Get full textAim. To reveal the association of polymorphic types of Toll-like receptor genes with myocardial infarction (MI), stroke in patients with coronary heart disease (CHD).Material and methods. Totally 292 patients studied, with CHD and anamnesis of stroke and/or MI. The association of 8 polymorphic loci...
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Soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) and polymorphic variants of TREM-1 in the development of multiple organ dysfunction syndrome after coronary ar...
Published 2019-07-01Get full textThe onset of critical complications (multiple organ dysfunction syndrome, MODS) after coronary artery bypass grafting is the result of severe stress response. The key etiopathological factor of the induction phase of the complex pathological process, which ultimately leads to dysfunction of organs a...
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ASSOCIATION OF A LYMPHOTOXIN-α VARIABLE SITE rs1041981 WITH DEVELOPMENT OF LONG-TERM UNFAVORABLE OUTCOMES IN PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ST-SEGMENT ELEVATION
Published 2018-01-01Get full textLymphotoxin-α (LTA) is a major pro-inflammatory cytokine produced at the early stages of vascular inflammation, taking part in the formation of arterial atherosclerosis and development of coronary heart disease. Functional changes in the gene encoding LTA production may influence the development of...
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Features of in-hospital clinical course of pulmonary embolism in patients of different age groups
Published 2020-11-01Get full textAim. To study the clinical course and management of patients with pulmonary embolism (PE) of various age groups hospitalized in a cardiology hospital.Material and methods. This prospective single-center study in the period from 2016 to 2018 included 154 patients with PE verified by computed tomograp...
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Type 2 myocardial infarction: the potential for early detection
Published 2023-04-01Get full textAim. To evaluate the potential of using factors associated with type 2 myocardial infarction (MI) for its early diagnosis.Material and methods. This prospective study included 204 patients diagnosed with acute coronary syndrome (ACS). At the time of admission, each patient underwent standard examina...
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