Search Results - I. I. Shaposhnik

Aim. To study the prognostic significance of various markers of atherosclerosis of lower limb arteries (LLA) in patients at high and very high cardiovascular risk (CVR).Methods. The study included 108 patients at high and very high CVR, the median age of which was 62.0 (55.7; 67.0) years. All patien...

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Aim. Based  on the results  of a long-term  follow-up, to determine  the clinical variants  of  hypertrophic  non-obstructive cardiomyopathy  (HNOCM) and  develop criteria for the progression of the disease.Material and methods. The results of long-term follow-up were evaluated  for 97 patients  wit...

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Aim. To present up-to-date information on the possibility of using statins in patients with inflammatory bowel disease (IBD).Highlights. Statins exhibit immunomodulatory effects, which are of particular importance with regard to IBD treatment. Experimental studies, which demonstrate positive effects...

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Aim. To study the prognostic significance of atherosclerosis of one and several vascular systems in patients with high and very high cardiovascular risk (CVR).Material and methods. The study included 171 patients with high (26,9%) and very high (73,1%) CVR. All patients underwent duplex ultrasound o...

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Aim.  To study muscular (brachial and radial arteries) and elastic (aorta) regional arterial stiffness in IBD patients in comparison with those without IBD, as well as to establish the relationship between arterial stiffness and the characteristics of the IBD course (the duration of illness, severit...

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Aim. To investigate the prognostic significance of the Atherosclerosis Burden Score (ABS) in relation to the development of major adverse cardiovascular events in patients of different cardiovascular risks (CVR) aged 40 to 64 years.Material and methods. Men and women aged 40 to 64 years were include...

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Aim. To present the methodological techniques for teaching deontology to students in modern clinical practice on the example of managing patients with cardiovascular diseases.Material and methods. We outlined the lectures and practical classes introduced into teaching fourth-year students within the...

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Heart rhythm disorders are considered as changes in the normal frequency, regularity, and source of depolarization of the heart, as well as impulse conduction disorders. Cardiac arrhythmias can be caused by numerous reasons, as well as their combination. The review presents current data on the frequ...

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Aim. To study the role of duplex ultrasound (DU) of carotid and lower extremity arteries in the restratification of cardiovascular risk (CVR) and changing the indications for lipid-lowering therapy.Material and methods. The study included 291 patients aged 40-64 years without established atheroscler...

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Introduction. At the current stage of the study of atherosclerosis, it has been established that chronic activation of innate immunity, causing persistent low-intensity sterile inflammation, plays a crucial role at all stages of atherogenesis. Laboratory evaluation of signaling pathways associated w...

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Aim. To assess the morphometric characteristics of Achilles tendons in patients with familial hypercholesterolemia (FH) and to identify factors associated with an increase in their size.Материал и  методы. Totally, 100 patients included, with severe primary hyperlipidemia, defined as an increase in...

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on behalf of the Committees of the Russian Society of Cardiology for work with medical schools of the Russian Federation and for educational activities and youth policyCardiovascular diseases take a leading place in the morbidity pattern worldwide, and therefore improving the cardiology education in...

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The data on the prognostic significance and relationship of the prolonged QT syndrome with the risk of cardiac rhythm disturbances in liver cirrhosis are contradictory. One of the directions of further research in this area is to study the significance of other electrocardiographic parameters reflec...

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Aim. To study the prognostic significance of abdominal aorta (AA) diameter in progression of peripheral atherosclerosis in patients aged 40-64 years and without abdominal aortic dilation.Materials and Methods. The study included 157 outpatients aged 40-64 years who underwent Doppler ultrasonography...

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Chronic non-infectious inflammation of low intensity is the most important mechanism of development and progression in atherosclerosis. Under the conditions of persistent non-resolving inflammation observed in the vascular wall and atherosclerotic plaque (ASB), permanent tissue damage occurs, thus l...

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The last fifteen years have been marked by rapid progress in the study of neutrophils. The discovery of transcriptional plasticity of neutrophils, their phenotypic and functional heterogeneity contributed to launching active interdisciplinary studies on the role of neutrophils in various chronic inf...

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Expert Council opinion describes emergency care in a sudden individually significant blood pressure (BP) increase without clinically overt target organ damage. In the new guidelines of the Russian Society of Cardiology, the term “hypertensive urgency” was abolished, and the management of a sudden BP...

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Aim. In practice, to evaluate the efficacy, safety and long-term adherence to therapy with a fixed-dose combination of ramipril/indapamide (Konsilar-D24) in patients with grade 1-2 hypertension (HTN) who have not achieved blood pressure (BP) control with prior therapy or have not taken antihypertens...

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The meeting of the expert council of cardiologists-lipidologists, organized with the support of Novartis and dedicated to the discussion of the existing system of medical care for patients with familial hypercholesterolemia / mixed dyslipidemia, the modern evidence base for lipid-lowering therapy an...

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Aim. To evaluate the diagnostic and prognostic value of circulating mature and aging neutrophils in relation to hypoechoic carotid plaques and short-term progression of carotid and multifocal atherosclerosis.Material and methods. The study included 200 patients (89 males and 111 fe­males), aged 40-6...

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