Search Results - I. G. Nikitin

Cardiorenal syndrome in patients with heart failure is a regular link in the chain of cardiorenal continuum. Physicians of various specialties may encounter patients with cardiorenal syndrome: general practitioners, cardiologists, nephrologists, resuscitators, anesthetists, cardiac surgeons, etc. Th...

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Hypertension is one of the key risk factors for cardiovascular morbidity and mortality. Metabolic syndrome (synonyms: syndrome X, insulin resistance syndrome) is characterized by increased visceral fat mass, decreased sensitivity of peripheral tissues to insulin (insulin resistance) and hyperinsulin...

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Ammonia belongs to the common neuro- and cytotoxic metabolites in the human. It is established that ammonia has hepatotoxic properties. Ammonia induces the formation of oxygen active forms, reduces the activity of endothelial NO synthase, dose-dependently decreases the cellular metabolism and prolif...

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The American College of Cardiology and the American Heart Association updated the guideline for the prevention, detection, evaluation and management of high blood pressure in adults in 2017 The European Society of Cardiology and the European Society оf Hypertension updated guidelines for the managem...

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The combination of heart failure and renal failure is called cardiorenal syndrome. It is a stage of the cardiorenal continuum and, possibly, a small link of the cardiorenal-cerebral-metabolic axis. Despite the fact that the phrase “cardiorenal syndrome” and its five types have become a part of the m...

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Despite a significant number of publications devoted to the care of patients with chronic heart failure (CHF), a practicing doctor is not always easy to navigate in the use of medicines and indications for high-tech methods of treatment in these patients. The largest evidence base is currently accum...

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Background: assessment of type, prevalence and duration of residual symptoms after COVID-19 in recent studies is controversial because of differences in design. Aim: to assess the prevalence and severity of symptoms in the long-term period after COVID-19. Materials and methods: patients hospitalized...

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An outbreak of unknown pneumonia, caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), was reported in China at the end of December 2019. On February 11, 2020, the World Health Organization officially named SARS-CoV-2 infection COVID-19 (Coronavirus Disease 2019). The most...

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The article is a lecture on modern recommendations of the European Society of Cardiology and the American Heart Association for the diagnosis of syncopal conditions. The article presents the latest information from the 2018 review concerning the definition of syncope, its classification, diagnostics...

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Acute heart failure (AHF) and acute decompensation of chronic heart failure (ADHF) are urgent health problems. The main tasks of the managing the patients with these conditions include the achieving of optimal and stable resolution of edema and dyspnea, the tissue perfusion improving, the severity o...

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Background: computer tomography (CT) features of COVID-19, their temporal changes and differences from other pulmonary (viral and bacterial pneumonia) and non-pulmonary diseases are well described in recent publications. The prevalence and characteristics of signs of concomitant problems that could...

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The article contains a clinical description of the case of combination of such two opposite states as obesity and malnutrition in a patient with chronic pancreatitis. The patient was hospitalized with exacerbation of chronic pancreatitis and alcohol abuse. The examination revealed exocrine pancreati...

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High efficacy of contemporary chemical and radiation treatments made it to success in treatment of oncohematological diseases. The fundamentals of many schemes of polychemotherapy of the first line are anthracyclines. Effective treatment of the main disease in many cases is followed by a variety of...

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Patients with chronic liver diseases (CLD) are at high risk of infection and severe COVID-19 (Corona Virus Disease).Aim: to create a database of patients with CLD, including an analysis of the frequency of detection of SARS-CoV-2 markers, the causes of hospitalization, an assessment of 30-day mortal...

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Aim. To study volumetric and linear parameters of the left atrium (LA) in operated and non-operated patients with severe  aortic stenosis  (AS) in comparison  with the control group of a similar age and gender.Material and methods. Eighty-one patients with AS were examined, 49 patients — in the long...

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Aim: To estimate the frequency of occurrence malnutrition and efficacy its correction in chronic pancreatitis (CP).Materials and methods: 148 patients were examined. Group I included 71 people with chronic alcoholic pancreatitis (CAP); group II — 77 patients with chronic obstructive pancreatitis (CO...

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The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpos...

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Cardiac amyloidosis (amyloid cardiomyopathy) is a disease damage to the heart caused by extracellular amyloid deposition. In some cases, there may be local damage to the structures of the heart, for example, the atria; more often, heart damage is part of a systemic (generalized) pathology. Depending...

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Biomarkers (various laboratory biochemical markers), such as natriuretic peptides (NP), soluble ST2 receptor, copeptin, galectin-3, are widely studied in patients with chronic heart failure (CHF). The European Society of Cardiology recommends the determination of blood NP level in suspicion of HF an...

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Nonalcoholic fatty liver disease (NAFLD) is currently a serious medical and social problem for public health systems due to its high prevalence, potential development of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). In addition, the presence of NAFLD in the patient’s somatic continuum is...

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