Search Results - Huijie Bian

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  1. 1
    hCCL19-expressing recombinant Newcastle disease virus boosts CAR T cell infiltration and efficacy in solid tumor

    hCCL19-expressing recombinant Newcastle disease virus boosts CAR T cell infiltration and efficacy in solid tumor by Qian Li, Ling Wang, Man Liu, Ze-kun Liu, Wen Yin, Can Li, Lan-Ting Feng, Ren-Yu Zhang, Wen-Liang Li, Hai-Jiao Yang, Yu-Le Yong, Xiang-Min Yang, Hong-Yong Cui, Ling-Min Kong, Zhi-Nan Chen, Huijie Bian, Ding Wei

    Published 2025-07-01

    Background Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematological malignancies; however, it faces significant challenges in treating solid tumors, including limited immune infiltration into tumor tissues and immunosuppressive tumor microenvironment. Oncolyti...

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  2. 2
    CD36 promotes iron accumulation and dysfunction in CD8 T cells via the p38-CEBPB-TfR1 axis in earlystage hepatocellular carcinoma

    CD36 promotes iron accumulation and dysfunction in CD8 T cells via the p38-CEBPB-TfR1 axis in earlystage hepatocellular carcinoma by Yifei Qin, Fei Huo, Zhuan Feng, Jialu Hou, Yaxin Ding, Quancheng Wang, Yu Gui, Ziwei Yang, Jiali Yang, Gang Zhou, Ling Li, Jianli Jiang, Lingmin Kong, Shijie Wang, Gang Nan, Dingqiao Xu, Xiaohang Xie, Lijuan Wang, Qian He, Ruibin Yang, Peng Lin, Huijie Bian, Zhi-Nan Chen, Jiao Wu

    Published 2025-07-01

    Background/Aims The identification of factors that lead to CD8+ T cell dysfunction within the tumor microenvironment (TME) holds great promise for the development of innovative immunotherapies. However, the mechanisms underlying the exhausted phenotype of CD8+ T cells infiltrating early-stage hepato...

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