Search Results - Huanhuan Hu

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    Ferroptotic Pathway Activation in Spermatogonia: A Novel Mechanism of Busulfan-Induced Testicular Injury

    Ferroptotic Pathway Activation in Spermatogonia: A Novel Mechanism of Busulfan-Induced Testicular Injury by Huanhuan Hu, Wenzheng Yuan, Yulin Wang, Zimei Dong, Guangwen Chen

    Published 2025-05-01

    Busulfan (BU) is a widely used chemotherapy drug that has been shown to cause reproductive functional impairment in humans and model animals. However, the precise mechanisms underlying testicular injury induced by BU exposure have not been fully elucidated. Ferroptosis is a form of programmed cell d...

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    Single-cell RNA sequencing reveals altered immune and stromal landscape in primary and liver metastasis of gastric cancer

    Single-cell RNA sequencing reveals altered immune and stromal landscape in primary and liver metastasis of gastric cancer by Bin Zhou, Xiaolin Liu, Huanhuan Hu, Zhipeng Li, Shanliang Zhong

    Published 2025-09-01

    Background: We aimed to identify stromal cells associated with liver metastasis of gastric cancer (GC). Methods: We downloaded single-cell RNA sequencing (scRNA-seq) datasets for GC tissues and adjacent normal tissues (NT), as well as liver metastases (LM) and healthy liver tissues (HL) from GEO. Ad...

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