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    The effect of ubiquitination and deubiquitination to imatinib resistance in gastrointestinal stromal tumors

    The effect of ubiquitination and deubiquitination to imatinib resistance in gastrointestinal stromal tumors by Huade Huo, Huade Huo, Haolin Li, Haolin Li, Xinlin Yang, Shu Wang, Shu Wang, Yan Zhao, Yan Zhao, Jianjun Yang, Jianjun Yang

    Published 2025-07-01

    Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor. Imatinib, as a receptor-type tyrosine kinase inhibitor (TKI), becomes a first-line drug for adjuvant therapy and prognosis. However, patients are facing with the problem of primary and secondary drug resistance when using im...

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