Search Results - Hong-jie FAN
-
1
Advances in pathogenesis of Streptococcus suis serotype 2
Published 2017-12-01Get full textStreptococcus suis is one of the major pathogens of swine streptococcosis. Among them, the strongest virulence and highest rate of clinical isolation serotype is S. suis serotype 2 (SS2). Moreover, SS2 is also an important zoonosis pathogen, which caused severe public health issues in China. It has...
Article -
2
Identification and Characterization of Putative Virulent Genes in Streptococcus equi ssp. zooepidemicus
Published 2013-02-01Get full textSuppression subtractive hybridization (SSH) was performed with virulent strain ATCC35246 and avirulent strain ST171 to identify novel genes associated with virulence in Streptococcus equi ssp. zooepidemicus (SEZ). There were fourteen genomic regions that only presented in virulent strain ATCC35246....
Article -
3
The vital role of covS in the establishment of Streptococcus equi subsp. zooepidemicus virulence
Published 2023-02-01Get full textStreptococcus equi subsp. zooepidemicus (SEZ) is an important zoonotic agent. Here, a virulence-attenuated strain M35246 derived from natural variation of wild-type SEZ ATCC35246 was found. M35246 showed a deletion of 25 contiguous genes as well as a loss-of-function mutation in covS. Subsequently,...
Article -
4
Evaluating the efficacy of an attenuated Streptococcus equi ssp. zooepidemicus vaccine produced by multi-gene deletion in pathogenicity island SeseCisland_4
Published 2019-05-01Get full textStreptococcus equi ssp. zooepidemicus (SEZ) is a pathogen associated with a wild range of animal species. Frequent outbreaks have occurred in recent years in pigs, horses, goats and dogs which is liable to infect humans. There is a lack of efficient vaccines against this disease and the occurrence o...
Article -
5
Preparation and application of a novel monoclonal antibody specific for the heat shock protein 60 of Lawsonia intracellularis
Published 2023-09-01Get full textPorcine proliferative enteropathy (PPE), an important infectious disease in pig production caused by an obligate intracellular bacterium Lawsonia intracellularis, is commonly associated with diarrhea and reduced weight gain in growing pigs widespread. An accurate method for detecting L. intracellula...
Article -
6
Insertion site of FLAG on foot-and-mouth disease virus VP1 G-H loop affects immunogenicity of FLAG
Published 2018-07-01Get full textThe G-H loop of the foot-and-mouth disease virus (FMDV) virion contains certain dominant immunogenic epitopes, as well as an arginine-glycine-aspartic acid (RGD) motif that is recognized by cell surface integrin receptors. Previous experiments indicate that it is critical to maintain virus structura...
Article -
7
Molecular epidemiology, characterization of virulence factors and antibiotic resistance profile of Streptococcus agalactiae isolated from dairy farms in China and Pakistan
Published 2023-05-01Get full textStreptococcus agalactiae is one of the most common pathogens that cause bovine mastitis worldwide. Identifying pathogen prevalence and virulence factors is critical for developing prevention and control approaches. Herein, 1 161 milk samples from various dairy farms in China (n=558) and Pakistan (n=...
Article