תוצאות חיפוש - Hideto To

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    Nasal Residence Depending on the Administered Dosage Form: Impact of Formulation Type on the In Vivo Nasal Retention Time of Drugs in Rats מאת Daisuke Inoue, Yoshihiro Seto, Hideto To

    יצא לאור 2025-06-01

    <b>Background/Objectives</b>: The precise control of drug absorption through the nasal mucosa following intranasal administration can be achieved through optimal formulation development that considers the nasal retention properties of the administered dosage form. This study aimed to qua...

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    A rare case of simultaneous rectal and gastric carcinomas accompanied with inferior mesenteric arterioportal fistula: case report מאת Kengo Kai, Koichiro Sano, Kazuhiro Higuchi, Shuichiro Uchiyama, Hideto Sueta, Atsushi Nanashima

    יצא לאור 2019-05-01

    Abstract Background Inferior mesenteric arterioportal fistula (APF) is rare as only 35 case reports in the literature. We herein presented a case of simultaneously double cancer in the rectum and stomach with inferior mesenteric APF, which is the first case report by searching using PubMed. Combinat...

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    Impacts of homoepitaxial AlN thickness on the qualities of AlGaN QWs fabricated on the face-to-face annealed sputter-deposited AlN templates מאת Ryota Akaike, Kenjiro Uesugi, Kohei Shima, Shigefusa F. Chichibu, Akira Uedono, Takao Nakamura, Hideto Miyake

    יצא לאור 2025-01-01

    AlGaN quantum wells (QWs) emitting at 265 nm were fabricated on face-to-face annealed sputter-deposited AlN (FFA Sp-AlN) templates with n-AlGaN and different homoepitaxial AlN thicknesses (200–2000 nm) by metalorganic vapor phase epitaxy (MOVPE). Thicker MOVPE-AlN led to higher dislocation densities...

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    Ultramicroporous Tröger's Base Framework Membranes With Ionized Sub‐nanochannels for Efficient Acid/Alkali Recovery מאת Haopan Sun, Ning Gan, Yuqing Lin, Baolong Wu, Yulong Qiu, Jingwen Su, Ziding Zhou, Fengyin Zou, Jianguo Yu, Hideto Matsuyama

    יצא לאור 2025-03-01

    Abstract Membrane technology holds significant potential for the recovery of acids and alkalis from industrial wastewater systems, with ion exchange membranes (IEMs) playing a crucial role in these applications. However, conventional IEMs are limited to separating only monovalent cations or anions,...

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    Recurrence with pagetoid spread arising 17 years after surgery for intramucosal rectal cancer: a case report מאת Taichi Matsubara, Yuta Kasagi, Kippei Ogaki, Yu Nakaji, Ryota Nakanishi, Yuichiro Nakashima, Masahiko Sugiyama, Hideto Sonoda, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara

    יצא לאור 2017-07-01

    Abstract Background Perianal Paget’s disease (pPD) is uncommon, with only about 180 cases documented in the literature. Anorectal carcinoma with pagetoid spread is even rarer. Case presentation An 81-year-old woman underwent rectal cancer extirpation with a transanal approach 17 years prior. She has...

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    A case of duodenal duplication cyst mimicking a pancreatic pseudocyst with intracystic hemorrhage מאת Sotaro Fukuhara, Saburo Fukuda, Hiroyuki Sawada, Masayuki Shishida, Sho Ishikawa, Kohata Akihiro, Azusa Kai, Yuzoh Hirata, Seiji Fujisaki, Mamoru Takahashi, Hideto Sakimoto

    יצא לאור 2019-05-01

    Abstract Background Duodenal duplication cysts in adults are rare, and a preoperative diagnosis remains difficult because clinical manifestations are nonspecific and variable. We describe a case of a duodenal duplication cyst mimicking a pancreatic pseudocyst with repeated intracystic hemorrhage. Ca...

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    Pembrolizumab for treatment-related neuroendocrine prostate carcinoma with a high tumor mutational burden: a case report מאת Keiji Shiba, Motohiro Fujiwara, Ayaka Onuki, Daisuke Kato, Takeshi Shirakawa, Yohei Shimizu, Takumasa Amemiya, Tsunehiro Nenohi, Yuki Matsumoto, Masayasu Urushibara, Hideto Kano, Kazuhiro Ishizaka, Mikiko Takahashi, Minato Yokoyama

    יצא לאור 2025-08-01

    Pembrolizumab has emerged as a significant therapeutic option for the treatment of solid tumors with a high tumor mutational burden (TMB-high). However, there have been no reports of its use in treatment-related neuroendocrine prostate carcinoma (t-NEPC) with TMB-high. We present the case of a 66-ye...

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    Randomised, double-blind, phase III study comparing the infliximab biosimilar, PF-06438179/GP1111, with reference infliximab: efficacy, safety and immunogenicity from week 30 to we... מאת Goran Babic, Hideto Kameda, Rieke Alten, Bogdan Batko, Tomas Hala, Sebastiao C Radominski, Vira Tseluyko, Carol Cronenberger, Sarah Hackley, Muhammad Rehman, Oliver von Richter, Min Zhang, Stanley Cohen

    יצא לאור 2019-05-01

    Objective To investigate the efficacy, safety and immunogenicity of PF-06438179/GP1111 (PF-SZ-IFX) compared with European reference infliximab (Remicade®; ref-IFX) in patients with moderate-to-severe, active rheumatoid arthritis after continued long-term use of PF-SZ-IFX, and in patients who were sw...

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    First evidence of tick-borne encephalitis (TBE) outside of Hokkaido Island in Japan מאת Masayuki Ohira, Kentaro Yoshii, Yasuhiro Aso, Hideto Nakajima, Toru Yamashita, Ikuko Takahashi-Iwata, Norihisa Maeda, Katsuro Shindo, Toshihiko Suenaga, Tohru Matsuura, Kazuma Sugie, Tadanori Hamano, Akira Arai, Rikiya Furutani, Yasuhiro Suzuki, Chikako Kaneko, Yasuhiro Kobayashi, Eduardo Campos-Alberto, Lisa R. Harper, Juanita Edwards, Cody Bender, Andreas Pilz, Shuhei Ito, Frederick J. Angulo, Wilhelm Erber, Harish Madhava, Jennifer Moïsi, Luis Jodar, Hidehiro Mizusawa, Masaki Takao

    יצא לאור 2023-12-01

    Tick-borne encephalitis (TBE) is an infection of the central nervous system caused by the tick-borne encephalitis virus (TBEV). TBE is endemic in parts of Europe and Asia. TBEV is transmitted to humans primarily by Ixodes ticks. There have been 5 TBE cases identified in Japan, all on the northern is...

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