Sökresultat - Helian Yang

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  1. 1
    Orphan Nuclear Receptors TR2 and TR4 in Erythropoiesis: From Mechanisms to Therapies

    Orphan Nuclear Receptors TR2 and TR4 in Erythropoiesis: From Mechanisms to Therapies av Yunlong Liu, Helian Yang, Mengtian Ren, Qing Yu, Qingyang Xu, Xiuping Fu

    Publicerad 2025-05-01

    Testicular orphan receptors TR2 and TR4 serve as central regulators of erythropoiesis, orchestrating the entire continuum of erythroid progenitor cell proliferation, differentiation, and maturation. As core components of the direct repeat erythroid determinant (DRED) complex, they activate erythroid...

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    Conditional Deletion of Translin/Trax in Dopaminergic Neurons Reveals No Impact on Psychostimulant Behaviors or Adiposity

    Conditional Deletion of Translin/Trax in Dopaminergic Neurons Reveals No Impact on Psychostimulant Behaviors or Adiposity av Yunlong Liu, Renkun Wu, Gaiyuan Geng, Helian Yang, Chunmiao Wang, Mengtian Ren, Xiuping Fu

    Publicerad 2025-07-01

    Despite the abundant expression of the microRNA-degrading Translin (TN)/Trax (TX) complex in midbrain dopaminergic (DA) neurons and its implication in neuropsychiatric disorders, its cell-autonomous roles in metabolic and behavioral responses remain unclear. To address this, we generated DA neuron-s...

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