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Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations. mā Sarah A Taylor, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Kyle D Gromer, Hiam Abdala-Valencia, Kiwon Nam, Salina T Dominguez, Anna B Montgomery, Paul A Reyfman, Lorena Ostilla, Joshua B Wechsler, Carla M Cuda, Richard M Green, Harris Perlman, Deborah R Winter
I whakaputaina 2021-01-01

<h4>Background & aims</h4>Limited understanding of the role for specific macrophage subsets in the pathogenesis of cholestatic liver injury is a barrier to advancing medical therapy. Macrophages have previously been implicated in both the mal-adaptive and protective responses in obst...

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