Hakutulokset - Guohui Li
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Changes in runoff from major alpine watersheds on the Qinghai-Tibetan plateau: A review Tekijä Guohui Li, Zongxing Li, Baoqing Zhang, Zongjie Li
Julkaistu 2025-08-01Study region: The Qinghai-Tibetan Plateau (QTP). Study focus: Water resources in QTP are increasingly vulnerable to climate change, yet comprehensive understanding of runoff dynamics and their drivers remains limited. This study systematically evaluates: (1) shifts in runoff recharge mechanisms unde...
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Beyond proofreading: POLD1 mutations as dynamic orchestrators of genomic instability and immune evasion in cancer Tekijä Huiqing Chen, Jiayu Wei, Qi Tang, Guohui Li, Yajing Zhou, Zhen Zhu
Julkaistu 2025-06-01DNA polymerase delta (Pol δ) is a cornerstone of genomic stability, orchestrating DNA replication and repair through its catalytic subunit, POLD1. This subunit’s 3’–5’ exonuclease domain proofreads replication errors, ensuring fidelity. However, POLD1 mutations—particularly in this domain—disrupt th...
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Methylome and transcriptome joint analyses identify differentially expressed genes based on purebred and crossbred Tianjin-monkey Chicken Tekijä Shuli Xia, Guohui Li, Xianghua Zhao, Chenghao Zhou, Haitao Yu, Wei Han
Julkaistu 2024-12-01Tianjin-monkey Chicken is a locally bred naked neck poultry with limited population size. Herein, we intended to identify potential breed-related genes based on methylome and transcriptome analyses. Tianjin-monkey Chicken and Hy-line Brown Chicken were crossbred and the individuals were divided into...
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Genetic Diversity and Population Structure Analysis of <i>Luhua chickens</i> Based on Genome-Wide Markers Tekijä Qianwen Yang, Wei Han, Jun Yan, Chenghao Zhou, Guohui Li, Huiyong Zhang, Jianmei Yin, Xubin Lu
Julkaistu 2025-07-01The <i>Luhua chicken</i> is an outstanding local breed in China that has been placed under conservation due to the impact of specialized breeding and the widespread adoption of commercial varieties. As such, this study analyzed reproductive traits across three consecutive generations and...
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Microstructure and Mechanical Properties of Laser-Clad Inconel 718 Coatings on Continuous Casting Mold Copper Plate Tekijä Yu Liu, Haiquan Jin, Guohui Li, Ruoyu Xu, Nan Ma, Hui Liang, Jian Lin, Wenqing Xiang, Zhanhui Zhang
Julkaistu 2025-06-01Mold copper plates (Cr–Zr–Cu alloy) frequently fail due to severe wear under high-temperature conditions during continuous casting. To solve this problem, Inconel 718 coatings were prepared on the plate surface via laser cladding to enhance its high-temperature wear resistance. The results demonstra...
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