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    A cytoderm metabolic labeling TPAPy-Tre for real-time detection of vitality of Mycobacterium tuberculosis in sputum

    A cytoderm metabolic labeling TPAPy-Tre for real-time detection of vitality of Mycobacterium tuberculosis in sputum by Mengru Yang, Guiqin Dai, Dan Li, Pengfei Zhao, Senlin Zhan, Hongjuan Qin, Hongzhou Lu, Mingbin Zheng, Peize Zhang

    Published 2025-07-01

    ABSTRACT Early bactericidal activity is a vital measure in developing new tuberculosis (TB) drugs. Traditional methods, including colony-forming units (CFUs) and time to positivity (TTP), have limitations. This study aimed to evaluate the efficacy of TPAPy-Tre fluorescence microscopy in monitoring e...

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