Search Results - Guangwen Wang

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  1. 1
    A Strand-Specific Quantitative RT-PCR Method for Detecting vRNA, cRNA, and mRNA of H7N9 Avian Influenza Virus in a Mouse Model

    A Strand-Specific Quantitative RT-PCR Method for Detecting vRNA, cRNA, and mRNA of H7N9 Avian Influenza Virus in a Mouse Model by Bo Wang, Guangwen Wang, Yi-han Wang, Xuwei Liu, Manman Li, Huihui Kong, Hualan Chen, Li Jiang, Chengjun Li

    Published 2025-07-01

    Avian influenza virus (AIV) remains a persistent threat to both the poultry industry and human health. Among the AIV subtypes posing public health threats, H7N9 AIV is responsible for five epidemic waves of human infection in China. Here, a detection system based on a mouse model was established, wh...

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    ABTB1 facilitates the replication of influenza A virus by counteracting TRIM4-mediated degradation of viral NP protein

    ABTB1 facilitates the replication of influenza A virus by counteracting TRIM4-mediated degradation of viral NP protein by Wenjun Shi, Zhibo Shan, Li Jiang, Guangwen Wang, Xuyuan Wang, Yu Chang, Yuzhen Hu, Bo Wang, Qibing Li, Yihan Wang, Guohua Deng, Jianzhong Shi, Yongping Jiang, Xianying Zeng, Guobin Tian, Hualan Chen, Chengjun Li

    Published 2023-12-01

    Influenza A viruses (IAVs) continue to cause tremendous economic losses to the global animal industry and respiratory diseases and deaths among humans. The nuclear import of the vRNP complex, composed of polymerase basic protein 1 (PB1), polymerase basic protein 2 (PB2), polymerase acidic protein (P...

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