Search Results - Guang Liang
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MicroRNA-22 inhibits proliferation and promotes differentiation of satellite cells in porcine skeletal muscle
Published 2020-01-01Get full textPig is an important economic animal in China. Improving meat quality and meat productivity is a long time issue in animal genetic breeding. MicroRNAs (miRNAs) are short non-coding RNAs that participate in various biological processes, such as muscle development and embryogenesis. miR-22 differential...
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YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2
Published 2025-07-01Get full textAbstract Background Parkinson's disease (PD) is a common neurodegenerative movement disorder, mainly characterized by the degeneration and loss of dopaminergic neurons in the substantia nigra. Oxidative stress is considered to be a key contributor to dopaminergic neuronal degeneration, triggeri...
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Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis
Published 2025-07-01Get full textAbstract Atherosclerosis has an urgent need for new therapeutic targets. Protein kinases orchestrate multiple cellular events in atherosclerosis and may provide new therapeutic targets for atherosclerosis. Here, a protein kinase, WEE1 G2 checkpoint kinase (WEE1), promoting inflammation in atheroscle...
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