Search Results - Geraldine Merle

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    Multi-labeling strategy to enhance direct aptamer sensor sensitivity for detecting MUC1 tumor marker

    Multi-labeling strategy to enhance direct aptamer sensor sensitivity for detecting MUC1 tumor marker by Ashkan Koushanpour, Edward J. Harvey, Geraldine Merle

    Published 2025-08-01

    Aptamers hold great potential for point-of-care diagnostics (POC), but the complexity of sensor architectures and poor sensitivities in detecting small molecules remain challenging. In this study, we present a simple but effective approach to enhance the sensitivity of the electrochemical ap-tamer-b...

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    Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation

    Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation by Muskan Alad, Fajer Yousef, Laura M. Epure, Angelina Lui, Michael P. Grant, Geraldine Merle, Nicoletta Eliopoulos, Jake Barralet, John Antoniou, Fackson Mwale

    Published 2025-06-01

    Osteoarthritis (OA) is now widely recognized not merely as a cartilage-centric disease but as a multifactorial disorder affecting the entire joint as an organ, including the articular cartilage, subchondral bone, synovium, ligaments, menisci, and the innervating neural elements. This review explores...

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