Αποτελέσματα αναζήτησης - George F. Gao

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    Assessment of vaccinations and breakthrough infections after adjustment of the dynamic zero-COVID-19 strategy in China: an online survey από Shijie Qin, Yanhua Li, Likui Wang, Xin Zhao, Xiaopeng Ma, George F. Gao

    Έκδοση 2023-12-01

    Coronavirus disease 2019 (COVID-19) cases in China has grown rapidly after adjustment of the dynamic zero-COVID-19 strategy. However, how different vaccination states affect symptoms, severity and post COVID conditions was unclear. Here, we used an online questionnaire to investigate the infection s...

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    Longitudinal Trends and Drivers of Antimicrobial Resistance in <i>Campylobacter</i> Worldwide (1954-2023) από Shulei Jia, Xuebin Xu, Mengqi Qu, Yuhang Pei, Siqi Sun, Yue Liu, Wanting Dong, Yongfei Hu, Baoli Zhu, George F. Gao, Yanan Wang

    Έκδοση 2025-02-01

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    Facilitating Cross-border Viral Sequencing Through Nucleic Acid Sample Transport Using Dry Cards από Lili Wang, Qikai Yin, Alie Brima Tia, Fengyu Tian, Liping Gao, Kai Nie, Kang Xiao, Xuejun Ma, Xiaoping Dong, Doris Harding, Xiaozhou He, George F. Gao

    Έκδοση 2025-05-01

    (1) Background: A safe and effective nucleic acid sample transportation method was developed that is suitable for underdeveloped areas which lack advanced sequencing capabilities, specifically for virus genomic sequencing and infectious disease monitoring. (2) Methods: This study evaluated the use o...

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    Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer από Jiawei Guan, Hongchuan Liu, Yan Chai, Jie Yu, Jian Yao, Jing Wang, Zhiwei Pan, Jing Zhang, Yuehua Zhou, Hui Liu, Sheng Yao, Jianxun Qi, Hui Feng, George F. Gao, Qihui Wang, Yi Shi, Shuguang Tan

    Έκδοση 2023-12-01

    Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a critical inhibitory checkpoint molecule, and monoclonal antibodies (mAbs) targeting CTLA-4 that restore anti-tumor T cell immunity have achieved clinical success. Here, we report a humanized IgG1 mAb, namely JS007, with high binding affinity...

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    Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD από Yulei Li, Peipei Liu, Tianjiao Hao, Sheng Liu, Xi Wang, Yufeng Xie, Ke Xu, Wenwen Lei, Cheng Zhang, Pu Han, Ying Li, Xiyue Jin, Yu Huan, Yafei Lu, Rong Zhang, Xiaoyan Li, Xin Zhao, Kun Xu, Pu Liao, Xuancheng Lu, Yuhai Bi, Hao Song, Guizhen Wu, Baoli Zhu, George F. Gao

    Έκδοση 2023-12-01

    Highly contagious respiratory illnesses like influenza and COVID-19 pose serious risks to public health. A two-in-one vaccine would be ideal to avoid multiple vaccinations for these diseases. Here, we generated a chimeric receptor binding domain of the spike protein (S-RBD) and hemagglutinin (HA)-st...

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    Severe pigeon paramyxovirus 1 infection in a human case with probable post-COVID-19 condition από Shujuan Cui, Hui Xiong, Zhaomin Feng, Yanhui Chu, Chengli Que, Jingning Qin, Yang Pan, Kunyao Yu, Lei Jia, Xi Yao, Jiping Liao, Da Huo, Cuiyan Guo, Hao Zhao, Meng Xu, Yanan Tian, Qing Peng, Fu Li, Hui Xu, Runsheng Hong, Daitao Zhang, Guangfa Wang, Peng Yang, George F. Gao, Quanyi Wang

    Έκδοση 2023-12-01

    Pigeon paramyxovirus 1 (PPMV-1) is an antigenic host variant of avian paramyxovirus 1. Sporadic outbreaks of PPMV-1 infection have occurred in pigeons in China; however, few cases of human PPMV-1 infection have been reported. The purpose of this article is to report a case of severe human PPMV-1 inf...

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