Search Results - Geoffrey Liu

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  1. 1
    Efficacy and Safety Assessment of the Addition of Bevacizumab to Adjuvant Therapy Agents in Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Efficacy and Safety Assessment of the Addition of Bevacizumab to Adjuvant Therapy Agents in Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. by Fariba Ahmadizar, N Charlotte Onland-Moret, Anthonius de Boer, Geoffrey Liu, Anke H Maitland-van der Zee

    Published 2015-01-01

    <h4>Aim</h4>To evaluate the efficacy and safety of bevacizumab in the adjuvant cancer therapy setting within different subset of patients.<h4>Methods & design/ results</h4>PubMed, EMBASE, Cochrane and Clinical trials.gov databases were searched for English language studie...

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  2. 2
    Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer.

    Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer. by Jingxiong Xu, Wei Xu, Jiyeon Choi, Yonathan Brhane, David C Christiani, Jui Kothari, James McKay, John K Field, Michael P A Davies, Geoffrey Liu, Christopher I Amos, Rayjean J Hung, Laurent Briollais

    Published 2023-09-01

    Common genetic variants associated with lung cancer have been well studied in the past decade. However, only 12.3% heritability has been explained by these variants. In this study, we investigate the contribution of rare variants (RVs) (minor allele frequency <0.01) to lung cancer through two lar...

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  3. 3
    Patterns of Treatment and Real‐World Outcomes of Patients With Non‐small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations Receiving Mobocertinib: The EXTRACT Study

    Patterns of Treatment and Real‐World Outcomes of Patients With Non‐small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations Receiving Mobocertinib: The EXTRACT Study by Geoffrey Liu, Shi Feng Nyaw, Tony S. K. Mok, Hubert Curcio, Alexis B. Cortot, Tsz Yeung Kam, Renaud Descourt, Yin Kwan Chik, Parneet Cheema, James M. Gwinnutt, Eric N. Churchill, Justin Nyborn, Eileen Curran, Alexandra Savell, Yu Yin, Katie Chong, Yuka Tanaka‐Chambers, Julian Kretz, Jacques Cadranel

    Published 2025-02-01

    ABSTRACT Background Real‐world data regarding patients with non‐small cell lung cancer (NSCLC) with EGFR exon 20 insertion (ex20ins) mutations receiving mobocertinib are limited. This study describes these patients' characteristics and outcomes. Methods A chart review was conducted across three...

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  4. 4
    Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.

    Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study. by Robert Carreras-Torres, Mattias Johansson, Philip C Haycock, Kaitlin H Wade, Caroline L Relton, Richard M Martin, George Davey Smith, Demetrius Albanes, Melinda C Aldrich, Angeline Andrew, Susanne M Arnold, Heike Bickeböller, Stig E Bojesen, Hans Brunnström, Jonas Manjer, Irene Brüske, Neil E Caporaso, Chu Chen, David C Christiani, W Jay Christian, Jennifer A Doherty, Eric J Duell, John K Field, Michael P A Davies, Michael W Marcus, Gary E Goodman, Kjell Grankvist, Aage Haugen, Yun-Chul Hong, Lambertus A Kiemeney, Erik H F M van der Heijden, Peter Kraft, Mikael B Johansson, Stephen Lam, Maria Teresa Landi, Philip Lazarus, Loïc Le Marchand, Geoffrey Liu, Olle Melander, Sungshim L Park, Gad Rennert, Angela Risch, Eric B Haura, Ghislaine Scelo, David Zaridze, Anush Mukeriya, Milan Savić, Jolanta Lissowska, Beata Swiatkowska, Vladimir Janout, Ivana Holcatova, Dana Mates, Matthew B Schabath, Hongbing Shen, Adonina Tardon, M Dawn Teare, Penella Woll, Ming-Sound Tsao, Xifeng Wu, Jian-Min Yuan, Rayjean J Hung, Christopher I Amos, James McKay, Paul Brennan

    Published 2017-01-01

    <h4>Background</h4>Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to assess causality, may help to identify the metabolic drive...

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