Resultados de búsqueda - Ge Zhang

With the gradual warming of the global climate, the possibility and risk of large-scale sliding and collapse disasters of glaciers, large ice sheets, and thicker ice sheets have increased. Using the discrete element numerical method to analyze glacier stability is of great importance for polar disas...

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Obtaining stable ECG signals under both static and dynamic conditions, while ensuring comfortable wear, is a prerequisite for fabric-electrode applications. It is necessary to study the wearing pressure of fabric electrodes as well as their organizational structure. In this study, fabric electrodes...

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Abstract Muling River, situated amidst cultivated lands in Heilongjiang Province, northeastern China, has long been subjected to sand‐digging activities, resulting in severe damage to its riverbed. However, little research has been conducted on the impact of this disturbance on the status of fish co...

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ABSTRACT Proteolysis targeting chimeras (PROTACs) have emerged as a groundbreaking class of anticancer therapeutics. These bifunctional molecules harness the endogenous ubiquitin–proteasome system to facilitate the degradation of targeted proteins of interest (POIs). Notably, the clinical translatio...

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Perfluorooctanoic acid (PFOA) is not only a pressing environmental concern in oceans, but also in terrestrial ecosystems. However, little is known about its potential impacts on pollinators. Here, we evaluated the physical and biological effects of different concentrations of PFOA (0.1 and 1 mg/L) o...

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Abiotic stressors threaten honeybee health, jeopardizing pollination services critical to agriculture and biodiversity. Here, we identified the <i>AmVgR</i> gene, which encodes a member of the low-density lipoprotein receptor family, and examined its function in the response of <i>...

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IntroductionMold-derived contamination in cigar tobacco leaves causes severe economic losses and health risks due to mycotoxin production. This study aimed to identify early-warning biomarkers for mold and elucidate their interaction with fungal communities.MethodGas chromatography-ion mobility spec...

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Potato tuber moth (PTM) Phthorimaea operculella, also known as tobacco splitworm, is an important pest of tobacco plants. The knowledge on the interaction of tobacco plant volatiles and PTM behavior is limited. To clarify the effect of tobacco plant volatiles on the orientation and oviposition behav...

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To address the demands for resource utilization of Yellow River sediment and the durability requirements of engineering materials in cold regions, this study systematically investigates the mechanisms affecting the frost resistance of slag-Yellow River sediment geopolymers through the incorporation...

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Chronic irritant dermatitis predisposes to Th2 skewed allergic contact dermatitis. Chronic hand dermatitis due to wet work or childhood- onset irritant flexural dermatitis (AD) is associated with sensitization to weak or non-sensitizing antigens as defined by the local lymph node (LLN) assay. In abo...

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ABSTRACT: The Luan River is the most important water system in north-eastern Hebei Province, China and is located in the transitional zone of the Eastern Yan Mountains, North China Plain and Songliao Plain. The well-developed river terraces of its tributary, the Yixun River, provide excellent inform...

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Electro-optical materials are crucial for lasers and modulators applications. Perovskite ferroelectric crystals, characterized by oxygen octahedrons and superior dipole migration capabilities, are recognized for their high electro-optic coefficients. However, the application of perovskite ferroelect...

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ABSTRACT Background The Wnt/β‐catenin pathway and its bone‐specific inhibitor, sclerostin, play important roles in skeletal development and homeostasis. The humanized sclerostin antibody, romosozumab, can significantly increase bone mineral density (BMD) of patients with osteoporosis, but it may als...

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Heterosis is an important biological phenomenon, and it has been used to increase grain yield, quality and resistance to abiotic and biotic stresses in many crops. However, the genetic mechanism of heterosis remains unclear up to now. In this study, a set of 184 chromosome segment substitution lines...

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The binding affinity of aptamers to targets has a crucial role in the pharmaceutical and biosensing effects. Despite diverse post-systematic evolution of ligands by exponential enrichment (post-SELEX) modifications explored in aptamer optimization, accurate prediction of high-affinity modification s...

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Background Coronary artery disease is characterized by chronic immune‐inflammation, excessive endoplasmic reticulum (ER) stress, and platelet hyperactivity; however, whether there is a signaling hub linking these events remains unclear. Here, we identified that TREM2 (triggering receptor expressed o...

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Abstract Spontaneous oscillations on the order of several hertz are the drivers of many crucial processes in nature. From bacterial swimming to mammal gaits, converting static energy inputs into slowly oscillating power is key to the autonomy of organisms across scales. However, the fabrication of s...

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Abstract Background and Aims Inflammageing represents both a critical pathophysiological hallmark and independent risk factor for myocardial infarction (MI), with age‐related increases observed in MI incidence and severity of post‐MI ventricular remodelling. Novel therapeutic strategies targeting in...

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Introduction Studies of gestational weight gain (GWG) and adverse pregnancy outcomes seldom focus on low-to-middle-income countries (LMICs), despite their high burden of morbidity and mortality. We examined GWG patterns and adverse pregnancy outcomes in a consortium of pregnancy cohorts from LMICs.M...

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