Zoekresultaten - Frances M. K. Williams

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  1. 1
    Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study

    Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study door Maryam Kazemi Naeini, Maxim B. Freidin, Isabelle Granville Smith, Stephen Ward, Frances M. K. Williams

    Gepubliceerd in 2025-06-01

    ABSTRACT Background Chronic back pain (CBP) is a major cause of disability globally. While its etiology is multifactorial, specific contributing genetic and environmental factors remain to be discovered. Paraspinal muscle fat has been shown in human and preclinical studies to be related to CBP. One...

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  2. 2
    Evaluating the association of transient receptor potential cation channel subfamily A member 1 gene polymorphisms with pain sensitivity: results from an adaptive recall by genotype study

    Evaluating the association of transient receptor potential cation channel subfamily A member 1 gene polymorphisms with pain sensitivity: results from an adaptive recall by genotype... door Aidan P. Nickerson, Laura J. Corbin, Nicholas J. Timpson, Megan Nott, Oliver Blanshard, Katie Foy, Fang Fang Quek, Christopher Geddie, Keith Phillips, Frances M.K. Williams, Anthony E. Pickering, James P. Dunham

    Gepubliceerd in 2025-08-01

    Abstract. Objective:. This prospective, double-blind, adaptive recall-by-genotype study assessed the effects of nonsynonymous variation in transient receptor potential ankyrin 1 (TRPA1) on thermal and mechanical detection and pain thresholds before and after topical application of the TRPA1 agonist...

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