Search Results - Feng Sun

BackgroundThis study examines the impact of physical exercise on college students’ perceived social support, meaning in life, and suicidal ideation, and further investigates the mediating and sequential mediating roles of perceived social support and meaning in life in the association between physic...

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ABSTRACT Chronic infection with the hepatitis B virus (HBV) remains one of the primary drivers of the development of hepatocellular carcinoma (HCC), a highly aggressive malignancy with a grim prognosis. This study focused on the role of E1A‐binding protein p300 (EP300) in the malignant phenotype of...

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<h4>Background</h4>Published data on the relationship between matrix metalloproteinases (MMPs) polymorphisms and ovarian cancer risk have implicated inconclusive results. To evaluate the role of MMPs polymorphisms in ovarian cancer risk, a meta-analysis and systematic review were perform...

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<h4>Objective</h4>To synthesize current evidence of the impact of Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on hypoglycemia, treatment discontinuation and glycemic level in patients with type 2 diabetes.<h4>Design</h4>Systematic review and network meta-analysis.&l...

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The water table of the Zoige peatland has been reduced in recent decades due to climate change and human activities. However, as the biological indicators of soil environment, how the response of soil nematode communities to water table reduction was no clear. In this study, we conducted an in situ...

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Abstract Introduction The development of pancreatic ductal adenocarcinoma (PDAC) is closely tied with the immune system. C‐C motif chemokine ligands (CCL) were proved to lead to immune recruitment and training. Thus, we reckoned CCL2 to be the kernel of immune suppression in PDAC tissues. Methods We...

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Chronic obstructive pulmonary disease (COPD) and tuberculosis pose significant public health challenges, particularly in tuberculosis-endemic developing regions where their co-prevalence may exacerbate the disease burden of chronic airflow obstruction. This study aimed to investigate the impact of s...

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Abstract: The application of nitrogen (N) fertilizer to increase crop yields has a significant influence on soil methane (CH4) and nitrous oxide (N2O) emission/uptake. A meta-analysis was carried out on the effect of N application on (i) CH4 emissions in rice paddies, (ii) CH4 uptake in upland field...

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<h4>Aim</h4>The association between dipeptidyl peptidase-4 inhibitors (DPP-4is), a class of anti-diabetes, and bone fracture in patients with type 2 diabetes mellitus (T2DM) is unknown. This meta-analysis aimed to systematically evaluate the effects of DPP-4is on bone fracture in T2DM pa...

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<h4>Background</h4>Numerous studies have demonstrated the life-extending effect of caloric restriction. It is generally accepted that caloric restriction has health benefits, such as prolonging lifespan and delaying the onset and progression of CKD in various species, especially in roden...

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ABSTRACT: The Tibetan Plateau is characterized by complex geological conditions and a relatively fragile ecological environment. In recent years, there has been continuous development and increased human activity in the Tibetan Plateau region, leading to a rising risk of landslides. The landslide in...

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To ascertain the possibility of cultivating maize using biological nitrogen fixation (BNF) by leguminous green manure crops in maize/leguminous green manure intercropping systems, BNF and nitrogen (N) transfer were studied in Xining and Wuwei, two typical northwestern Chinese cities. The experimenta...

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The problem of bacterial resistance poses a significant threat to human and animal health as well as public safety, making the discovery of effective new antimicrobial compounds an urgent priority. Traditional methods for screening antimicrobial activity are often time-consuming and labor-intensive,...

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For clarifying the corrosion fatigue risk of drill pipe in service in Northwest Oilfield, the corrosion fatigue sensitivity of drill pipe was studied when there were defects with different depths on the surface of drill pipe by simulating the rotary bending corrosion fatigue test of drill pipe worki...

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BackgroundWhether specific antihypertensive treatments increase cancer risk in patients with hypertension is still controversial. We aimed to estimate the associations of different antihypertensive treatments with cancer risk in real-world settings.MethodsA longitudinal cohort study was designed in...

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Many mammalian herpes viruses utilize heparan sulfate (HS) moieties present on cell surface proteoglycans as receptors for cell entry, and this process also requires viral glycoprotein C (gC) homologues. However, our understanding of the role of gC in facilitating attachment of other alpha-herpes vi...

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CD8, a glycoprotein on the surface of T cells, is involved in the defense against viral infection and plays significant roles in antigen presentation and in the antiviral immune response. CD8 is composed of two chains. Of these, the CD8α chain was chosen for the detection because it involved in both...

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The capsid (Cap) protein, which is the only structural protein of duck circovirus (DuCV), is the most important antigen for the development of vaccines against DuCV and the virus's serological diagnostic methods. In order to use yeast expression system to produce a large quantities of DuCV Cap...

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Abstract BackgroundActive vaccine safety surveillance (AVSS) stands as a top priority for the World Health Organization (WHO), serving as a critical indicator of the fourth maturity level for national regulatory agencies. ObjectiveThis review aims to define the min...

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