Search Results - Feng GAO

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  1. 1

    Salicin inhibits AGE-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes: therapeutic potential in osteoarthritis by Feng Gao, Shanyong Zhang

    Published 2019-12-01

    Osteoarthritis (OA) is a major age-related disease, which may be caused by the accumulation of advanced glycation end-products (AGEs). Excessive degradation of type II collagen and aggrecan by matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin type 1 motif (...

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  2. 2

    Neural Network Method for Solving Time Fractional Diffusion Equations by Feng Gao, Chunmei Chi

    Published 2025-05-01

    In this paper, we propose a neural network method to solve time-fractional diffusion equations with Dirichlet boundary conditions by using a combination of machine learning techniques and Method of Lines. We first used the Method of Lines to discretize the equation in the space domain while keeping...

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  3. 3

    Active Region Design With Different Crystal Orientations for High-Speed DFB Laser by Jianwei Li, Feng Gao, Jia Zhao

    Published 2024-01-01

    High-speed directly modulated distributed feedback (DFB) laser is crucial for high-speed optical communication systems. The modulation bandwidth and frequency chirp of such devices are primarily affected by the differential gain and linewidth enhancement factor (LEF) of the quantum wells (QWs) in th...

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  4. 4

    Chronic obstructive pulmonary disease: in-depth analysis of microbiota association and innovative prevention and treatment approaches from the gut-lung axis perspective by Yubo Wang, Xinyu Li, Feng Gao

    Published 2025-07-01

    The pathogenesis of chronic obstructive pulmonary disease (COPD) is complex and affects multiple systems. This article focuses on COPD and elaborates on the roles of the lung and gut microbiota as well as preventive and therapeutic strategies. Innovatively, this article reveals the impact of the con...

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  5. 5

    Wetland Ecological Restoration and Geomorphological Evolution: A Hydrodynamic-Sediment-Vegetation Coupled Modeling Study by Haiyang Yan, Bing Shi, Feng Gao

    Published 2025-07-01

    This study developed a coupled hydrodynamic-sediment-vegetation model to investigate the effects of <i>Spartina alterniflora</i> management and <i>Suaeda salsa</i> restoration on coastal wetland geomorphological evolution and vegetation distribution. Special attention is paid...

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  6. 6

    Threshold effects of bone mineral density on mortality risk: a comprehensive analysis of BMI-mediated pathways in older population by Zifei Yin, Chen Kuang, Feng Gao, Feng Xu

    Published 2025-07-01

    BackgroundThe precise relationship between bone mineral density (BMD) and all-cause mortality in older adults remains incompletely understood. This study aimed to investigate the association between BMD and all-cause mortality and to explore the mediating role of body mass index (BMI) in adults aged...

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  7. 7

    Long-term effects of mild traumatic brain injury in pediatrics by Tumarisi Tuersunjiang, Qingchen Wang, Hongqiao Yang, Feng Gao, Zhengchun Wang

    Published 2025-08-01

    Mild traumatic brain injury (mTBI) is a prevalent injury among children, typically resolving within weeks or months. However, emerging evidence suggests that a subset of pediatric patients may experience long-term effects that impact cognitive, emotional, and behavioral functions. This review synthe...

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  8. 8

    Applications and advances of multi-omics technologies in gastrointestinal tumors by Yuqing Liu, Feng Gao, Yang Cheng, Liang Qi, Haining Yu

    Published 2025-07-01

    Gastrointestinal tumors pose a significant clinical challenge due to their high heterogeneity and the difficulties in early diagnosis. The article systematically reviews the latest advances in multi-omics technologies in gastrointestinal tumor research, focusing on their contributions to early scree...

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  9. 9

    Allelic Variation in Loci for Adaptive Response and Its Effect on Agronomical Traits in Chinese Wheat (Triticum aestivum L.) by Li-feng GAO, Pan LIU, Yan-chun GU, Ji-zeng JIA

    Published 2014-07-01

    Heading date was an important trait that decided the adaptation of wheat to environments. It was modified by genes involved in vernalization response, photoperiod response and development rate. In this study, four loci Xgwm261, Xgwm219, Xbarc23 and Ppd-D1 which were previously reported related to he...

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  10. 10

    Quality Assessment of Dual-Polarization C-Band SAR Data Influenced by Precipitation Based on Normalized Polarimetric Radar Vegetation Index by Jisung Geba Chang, Simon Kraatz, Yisok Oh, Feng Gao, Martha Anderson

    Published 2025-07-01

    Advanced Synthetic Aperture Radar (SAR) has become an essential modality in remote sensing, offering all-weather capabilities and sensitivity to vegetation biophysical parameters and surface conditions, while effectively complementing optical sensor data. This study evaluates the impact of precipita...

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  11. 11

    Influence of Principal Stress Orientation on Cyclic Degradation of Soft Clay Under Storm Wave Loading by Chengcong Hu, Feng Gao, Biao Huang, Peipei Li, Zheng Hu, Kun Pan

    Published 2025-06-01

    Coastal marine soft clays subjected to long-term storm wave loading often exhibit inclined initial principal stress orientation (<i>α</i><sub>0</sub>) and subsequent cyclic principal stress rotation (PSR). These stress states critically influence soil mechanical behavior and...

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  12. 12

    Research on Design and Energy-Saving Performance of Gate Rudder by Chunhui Wang, Qian Gao, Lin Li, Feng Gao, Zhiyuan Wang, Chao Wang

    Published 2025-05-01

    As a novel energy-saving and maneuvering device for ships, the gate rudder system (GRS) functions similarly to an accelerating duct. While providing additional thrust, its independently controllable rudder blades on either side of the propeller also enhance ship maneuverability. The GRS was first fu...

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  13. 13

    Comparison of two portable metabolic systems for measuring energy expenditure at rest and during exercise in untrained women by Feng Gao, Feng Gao, Feng Gao, Yujing Chan-Yu, Yujing Chan-Yu, Zhi Li, Zhi Li, Yongfu Liu, Yongfu Liu, Fei Liu, Fei Liu, Di Liu, Wenjun Yu, Wenjun Yu, Weiwei Chen, Junhua Wang, Junhua Wang, Junhua Wang, Shenglong Le, Shenglong Le, Shenglong Le

    Published 2025-07-01

    PurposePortable metabolic systems are used as the “gold standard” for measuring energy expenditure (EE) in the development and validation of wearable devices. This study aimed to compare EE measurements obtained using the COSMED K5 (K5) and CORTEX METAMAX 3B (M3B) during the resting state and submax...

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  14. 14

    Autoimmune polyglandular syndrome among Chinese celiac disease patients: a survey of 243 individuals in China by Shenglong Xue, Yan Feng, Yan Feng, Tian Shi, Tian Shi, Halina Halike, Halina Halike, Ayinuer Maimaitireyimu, Ayinuer Maimaitireyimu, Adilai Abudurexiti, Adilai Abudurexiti, Jinjin Xie, Shanxia Yao, Feng Gao, Feng Gao

    Published 2025-07-01

    BackgroundCeliac disease (CeD), an autoimmune enteropathy, is often associated with multiple glandular autoimmune diseases. However, the prevalence and staging characteristics of autoimmune polyglandular syndrome (APS) among CeD patients remain unclear. The aim of this study was to assess the preval...

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  15. 15

    Risk assessment of thyroid nodules with a multi-instance convolutional neural network by Da Yu, Tingting Song, Yancheng Yu, Hebin Zhang, Feng Gao, Zirong Wang, Jiacheng Wang

    Published 2025-07-01

    ObjectivesUltrasonography is the primary imaging modality for evaluating thyroid nodules, and artificial intelligence (AI) has advanced the automated diagnosis of thyroid cancer. However, existing AI-assisted methods often suffer from limited diagnostic performance.MethodsIn this study, we propose a...

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  16. 16

    LINC00461 promotes macrophage M1 polarization by inhibiting KLF4 transcription by Bicong Gao, Kaitong Jia, You Ya, Rui Tian, Xiaochen Wang, Zheng Huang, Feng Gao

    Published 2025-07-01

    Background: Macrophage polarization is a complex process whereby macrophages differentiate into M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotypes, mediating distinct and often opposing functions in immunity and tissue repair. Methods: We analyzed LINC00461 expression in M1- and M2-polarized...

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  17. 17

    An acute Q fever with vessel vasculitis: case report by Shijun Guo, Quanle Liu, Jiaqi Yan, Jin Wang, Yingran Zhong, Feng Gao, Yuejia Zhong

    Published 2025-07-01

    BackgroundQ fever (QF) is a relatively rare zoonotic infectious disease, and complications such as vasculitis and endocarditis are uncommon but severe. This article reports a case of acute QF complicated by vasculitis.Case presentationThe patient presented with a week of recurrent fever. Upon admiss...

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  18. 18

    Miniaturized BAW Filter for Wide Band Application Based on High-Q Factor Active Inductor by Zhencheng Xu, Jiabei Pan, Feng Gao, Weipeng Xuan, Hao Jin, Jikui Luo, Shurong Dong

    Published 2025-05-01

    BAW filters have been widely used in RF circuits, and their combination with integrated passive inductors is one of the most common forms of BAW filters. However, the large size of passive inductors increases the area of the filter, making it unable to meet packaging requirements. At the same time,...

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  19. 19

    Automated Optical Flow Based Registration for Adaptive Optics Scanning Laser Ophthalmoscope by Yiwei Chen, Yi He, Jing Wang, Wanyue Li, Lina Xing, Feng Gao, Guohua Shi

    Published 2020-01-01

    This study presents an automated registration method based on optical flow for an adaptive optics scanning laser ophthalmoscope. The method was designed to align and average images to obtain a higher signal-to-noise ratio image. A correlation based optical flow image registration method, which has l...

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  20. 20

    Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach by Ruofan Guo, Ruofan Guo, Guohua Yu, Yuan Li, Youyou Wang, Youyou Wang, Huixia Fan, Shuo Zhang, Chen Wang, Junhui Zhou, Junhui Zhou, Jian Yang, Jian Yang, Feng Gao, Feng Gao, Zhiqiang Luo

    Published 2025-07-01

    3,4,5-Trihydroxybiphenyl (THB) is a naturally occurring compound derived from Sorbus pohuashanensis, primarily reported for its antifungal activity. However, its potential to inhibit α-glucosidase remains unclear. In this study, we assessed the inhibitory effects of THB on α-glucosidase and explored...

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