Søgeresultater - Fangjun Li

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  1. 1
    The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson’s disease

    The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson’s disease af Mengyun Yue, Tingtao Chen, Wenjie Chen, Jing Wei, Bin Liao, Jie Zhang, Fangjun Li, Daojun Hong, Xin Fang

    Udgivet 2026-03-01

    Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration. Previous studies have shown that glucagon-like peptide-1 (GLP-1) has beneficial effects in a mouse model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. However, the effect of GLP-1...

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  2. 2
    Machine learning approach effectively discriminates between Parkinson’s disease and progressive supranuclear palsy: Multi-level indices of rs-fMRI

    Machine learning approach effectively discriminates between Parkinson’s disease and progressive supranuclear palsy: Multi-level indices of rs-fMRI af Weiling Cheng, Xiao Liang, Wei Zeng, Jiali Guo, Zhibiao Yin, Jiankun Dai, Daojun Hong, Fuqing Zhou, Fangjun Li, Xin Fang

    Udgivet 2025-09-01

    Aim: Parkinson’s disease (PD) and progressive supranuclear palsy (PSP) present similar clinical symptoms, but their treatment options and clinical prognosis differ significantly. Therefore, we aimed to discriminate between PD and PSP based on multi-level indices of resting-state functional magnetic...

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