Search Results - Fan Tong
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BERT2DAb: a pre-trained model for antibody representation based on amino acid sequences and 2D-structure
Published 2023-12-01Get full textPrior research has generated a vast amount of antibody sequences, which has allowed the pre-training of language models on amino acid sequences to improve the efficiency of antibody screening and optimization. However, compared to those for proteins, there are fewer pre-trained language models avail...
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Research on the Simulation Prediction and Evaluation of the Cathodic Protection Effect of Condensers
Published 2021-04-01Get full textAiming at evaluating the cathodic protection effect of the condenser system, a prototype of the condenser system was established, and the protection effect of the cathodic protection system was evaluated through experiments. Subsequently, the simulation and optimization of the condenser protection p...
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Nose-to-brain delivery of targeted lipid nanoparticles as two-pronged β-amyloid nanoscavenger for Alzheimer's disease therapy
Published 2025-06-01Get full textAlzheimer's disease (AD), characterized by β-amyloid (Aβ) aggregation and neuroinflammation, remains a formidable clinical challenge. Herein, we present an innovative nose-to-brain delivery platform utilizing lactoferrin (Lf)-functionalized lipid nanoparticles (LNPs) co-encapsulating α-mangosti...
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