Resultados de búsqueda - Fan Chen

In the greenhouse environment, factors such as variable lighting conditions, the similarity in color between fruit stems and background, and the complex growth posture of string tomatoes lead to low detection accuracy for picking points. This paper proposes a detection method for the synchronous rec...

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With the growing complexity and interdependence of urban systems, multi-objective optimization (MOO) has become a critical tool for smart-city planning, sustainability, and real-time decision-making. This article presents a systematic literature review (SLR) of 117 peer-reviewed studies published be...

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The ecological consequences of the construction and operation of the Three Gorges Reservoir, particularly its unique operation strategy of storing clear water and releasing turbid water, exerts a profound influence on the composition and dynamics of local fish communities. To date, detailed and comp...

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Recent studies suggested that microRNA-200 family microRNAs play critical roles in cancer initiation and metastasis. The underlying mechanism remained elusive. In this study, we show that microRNA-200c is upregulated in nasopharyngeal carcinoma cells. Manipulation of microRNA-200c levels affected ce...

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<h4>Background</h4>Postoperative pain resulting from surgical trauma is a significant challenge for healthcare providers. Opioid analgesics are commonly used to treat postoperative pain; however, these drugs are associated with a number of undesirable side effects.<h4>Objective<...

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Ischemic stroke (IS) is a leading cause of global morbidity and mortality. A critical strategy for improving the prognosis of IS involves mitigating neuronal loss to enhance neuroplasticity, with microglia playing a vital role in neuronal survival. The platelet activating factor receptor (PTAFR) par...

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Abstract Background Parkinson's disease (PD) is a common neurodegenerative movement disorder, mainly characterized by the degeneration and loss of dopaminergic neurons in the substantia nigra. Oxidative stress is considered to be a key contributor to dopaminergic neuronal degeneration, triggeri...

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BackgroundWalking is a fundamental and accessible physical activity (PA) for older adults. Using daily step counts to self-monitor adherence to the World Health Organization’s (WHO) PA guidelines may facilitate health promotion and promote behavioral changes. This study aimed to determine the step c...

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Working memory (WM) is a fundamental cognitive function crucial adaptive behavior. The intricate interplay between the frontal cortex and striatum in governing WM maintenance and updating remains a central question. In this study, we employed optogenetics to demonstrate that inhibiting both dorsomed...

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Summary: Oxidative stress is a “double-edged sword” in mediating cellular activities. Here, we report that Mist1+ cells are resistant to oxidative-stress-induced cell death and that persistent oxidative stress and Kras mutation act in Knudson’s “two-hit” paradigm to promote gastric cancer initiation...

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Background Despite the remarkable clinical outcomes of epidermal growth factor receptor (EGFR)-targeted therapies in patients with lung cancer, therapeutic resistance eventually develops. This study elucidates the role of galectin-9 (Gal-9), a TIM-3 immune checkpoint ligand, in facilitating tumor im...

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