Search Results - F. T. Ageev

The paper discusses modern aspects of epidemiology, pathogenesis, clinical course, diagnostics, and treatment of the patients with chronic heart failure (CHF) and intact left ventricular ejection fraction (LVEF). CHF with intact LVEF comprises over 50% of all CHF cases, and is more prevalent in elde...

Full description

Left ventricular hypertrophy (LVH) is regarded as the main predictor of cardiovascular mortality. “Remodeling” term, preceded by “LVH”, includes the whole complex of multi!level changes, from macroscopic to biochemical and genetic, associated with diastolic and systolic myocardial dysfunction, myoca...

Full description

Aim. To assess the clinical outcomes and tolerability of antihypertensive therapy with single pill combinations (SPC) amlodipine + telmisartan and hydrochlorothiazide + telmisartan in clinical practice.Material and methods. Patients with hypertension of grade 1-3 (n=13647; 57.6% women; age 59.3±11.4...

Full description

Type 2 diabetes mellitus is known to increase the risk of the development of heart failure with preserved ejection fraction and worsen its symptoms. To date, no specific treatment has been shown to reduce morbidity and mortality in patients with heart failure with preserved ejection fraction. In thi...

Full description

Background. Adherence in cardiological patients is a leading challenge due to a high society burden imposed by cardiovascular diseases (CVDs) through morbidity, reduced life expectancy, disability and high mortality rates in population. Despite the availability of highly effective medicines and high...

Full description

Aim. To compare clinical outcomes in patients with hypertension and atherosclerotic cardiovascular diseases (CVDs) prescribed a combination of buffered acetylsalicylic acid (BA) (Cardiomagnyl®) + Azilsartan/Azilsartan+chlorthalidone (Edarbi/Edarbi Clo®) or enteric-coated acetylsalicylic acid (ECA) +...

Full description

Recently published studies have demonstrated a direct link between heart rate (HR) and prognosis across various populations and clinical groups, including elderly people, patients with arterial hypertension, myocardial infarction, and coronary artery stenting, overweight patients, or even young peop...

Full description

The review presents modern views on pathogenetic mechanisms of myocardial hypertrophy, with the key role played by renin-angiotensin system (RAS) activation and hemodynamic overload. The authors analyze main structural and functional disturbances typical for and underlying the clinical manifestation...

Full description

Aim. To determine the reproducibility of the results of instantaneous wavefree ratio (iFR) and angiography coregistration in patients with coronary heart disease (CAD) with multilevel and diffuse lesions of the coronary arteries.Materials and methods. The study included 34 patients with chronic isch...

Full description

These guidelines were developed to improve the outpatient care service for patients with chronic heart failure by creating specialized offices in the structure of first-level medical organizations, whose staff includes specialized personnel of both senior and middle medical level.

The course of hypertension is often complicated by left ventricular hypertrophy (or hypertensive heart disease, HHD). The main “corridor” of natural HHD is development of heart failure with preserved ejection fraction (HFpEF). With HFpEF, the bioavailability of natriuretic peptides (NP) is significa...

Full description

Aim. To create an advanced algorithm for predicting cardiovascular events (CVE) in low/moderate risk patients using a complex of traditional and new factors.Material and methods. The study included 700 patients with Systematic Coronary Risk Evaluation (SCORE) <5%, examined in 20092010. In add...

Full description

Despite advances in pharma and high-technology medicine, the rate of burdensome hospital admissions and mortality in patients with chronic heart failure (CHF) remains high. Over half of all admission-entailing decompensations have been repeatedly shown to emerge from non-compliance with outpatient p...

Full description

The manifold studies on ACE gene impact on left ventricular hypertrophy (LVH) development in hypertrophic cardiomyopathy (HCMP) and arterial hypertension (AH) have provided too contradictory results to clarify the association between ACE gene I/D polymorphism and cardiovascular pathology in these no...

Full description

Aim. To assess the contribution of anxiety (A) and depression (D) to the increased risk of cardiovascular events (CVEs) in patients with Systematic Coronary Risk Evaluation (SCORE) <5% according to 10-year follow-up.Material and methods. The work included 190 patients with SCORErisk <5...

Full description

One of the causes of high mortality from cardiovascular diseases is the lack of effective measures for the primary and secondary prevention of cardiovascular complications (CCO), due to the difficulty of timely identification risk factors (RF) and individuals with a high individual risk of CCO. This...

Full description

The goal is to evaluate the efficacy and security of treatment of patients with arterial hypertension (AH) during the heat wave of a fixed combination of ARBS+ACC (losartan+amlodipine).Materials and methods. Included 26 patients with hypertension 1 and 2 degrees from 42 to 81 years. All patients und...

Full description

Background. The potential global warming justifies the need for further investigation of the impact of abnormally hot summer weather on health and the prevention of these negative health effects.Aim. To study the effects of extreme climatic conditions (hot weather) on hemodynamics, electrolyte metab...

Full description

The influence of abnormal summer heat (AH) in the year 2010 on morbidity and mortality in Russian Federation regions is not studied good enough. Nizhny Novgorod Oblast was one of the most involved and harmed.Aim. Retrospective assessment of short- and long-term influence of AH and fires of the summe...

Full description

Aim. To compare the effects of ACE inhibitors zofenopril and perindopril on endothelial function and oxidative stress (OS) in patients with stable CHD and AH. Material and methods. In total, 40 patients with stable CHD (Functional Class II-III effort angina) and Stage 1-2 AH received zofenopril (7,5...

Full description