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A Possible Association between Deep Molecular Response and Combination of Tyrosine Kinase Inhibitor and Immunochemotherapy in a Patient with Coexisting Chronic Myeloid Leukemia and...
Published 2025-04-01Get full textTyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML) and improved survival rates, however, concerns about TKI-related secondary malignancies persist. We report the case of a 55-year-old male with chronic phase CML who achieved a minimal molecular resp...
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Phosphorus fertilization alters complexity of paddy soil dissolved organic matter
Published 2020-09-01Get full textThe structural complexity of soil dissolved organic matter (DOM) may reflect soil biogeochemical processes due to its spectral characteristics. However, the features of DOM structural complexity in paddy soil amended with long-term chemical P fertilization are still unclear, which may limit understa...
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Isoliensinine Induces Ferroptosis in Urothelial Carcinoma Cells via the PI3K/AKT/HIF-1α Axis: Molecular Evidence from Next-Generation Sequencing
Published 2025-07-01Get full text<b>Background:</b> Bladder cancer ranks ninth among the most commonly diagnosed cancers, with urothelial carcinoma (UC) accounting for more than 90% of all cases. Given the high recurrence rate and progression risk of bladder cancer, investigating alternative adjunct therapies is imperat...
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