Search Results - E. V. Shlyakhto

Пациенты с мультифокальным атеросклерозом (МФА) имеют высокие показатели заболеваемости и смертности, в основном, из-за "больших" сердечно-­сосудистых событий....

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The article provides modern data on the prevalence of cardiovascular diseases and mortality in Europe and Russia. Groups of high-risk patients requiring special attention when conducting measures to reduce cardiovascular mortality are discussed: patients with hypertension, including resistant, patie...

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The review concerns on the experimental studies results of the influence of ischemic and pharmacological post conditioning of the liver, brain, myocardium and scelet muscle on the expression and activity of the hypoxia-induced factor-1α (HIF-1α) in various types of lab animals.

The review contains modern scientific literary data, recently conducted studies, which devoted to studying of molecular, cellular and genetic mechanisms in processes of angiogenesis. The authors describe in detail angiogenesis stages, value of the main proangiogenic and antiangiogenic factors, apopt...

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The results of the multi-center, open, titrating trial of rilmenidine «ALTAIR» (ALbarel: effectiveness and Tolerability in ArterIal hypeRtension) are demonstrated. Aim. To assess antihypertensive effectiveness and safety of rilmenidine as monotherapy and in combination with amlodipine in out-patient...

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In material from 1086 patients who underwent heart valve disease surgery, traditional hystologic assessment, argyrophilic nucleolar organizer analysis, with calculation of mean Ag granule number per endotheliocyte and fibroblast nucleus; immuno-hystochemical assay with monoclone antibodies to Entero...

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The ongoing pandemic caused by virus SARS-CoV-2 encourages the search for ways to save the population. Since people first encountered this disease, it is being actively studied, and updating medical information is extremely valuable. Since people first encountered this disease, it is being actively...

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Medical care improvement in Russan federation directly depends upon implementation to broad practice of professionally-public accreditation of professional   educational   programs   of  medical  profile.  Important  role  in  the evaluation of professional education and specialists preparing, inclu...

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Despite widespread knowledge in the management of patients with lipid metabolism disorders, their application in clinical practice is insufficient. Identification of barriers to the implementation of key principles of clinical guidelines in routine practice is the first step of the implementation st...

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A distinction of the physical exertion into phases is necessary for on-time decisionmaking of the correct clinical decisions in medicine and for evaluation of the level ofsportsmen professional preparedness in sport medicine.Aim. 1) To reveal the consequence of compensatory reactions in human bodydu...

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To assess prognostic value of chronic heart failure (CHF) severity markers in patients aged over 74 years, and to optimise the risk stratification accordingly. This prospective study included 104 CHF patients aged 75 years or older, who were followed up for 2,5 years after hospital discharge. The ef...

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Aim. To determine district-specific barriers to the implementation of key points of clinical guidelines on lipid metabolism disorders in practice, with a focus on identifying disagreements and inconsistencies in the perception of problems between health professionals in each district.Material and me...

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Published studies demonstrate insufficient implementation of clinical guidelines into actual clinical practice. Successful implementation of diagnostic and treatment guidelines for patients with lipid metabolism disorders directly depends on the identification of barriers and timely application of s...

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Aim. To study the frequency of administration of direct oral anticoagulant (DOACs) in doses recommended and not recommended by the instructions of the drugs in non-valve atrial fibrillation (AF) patients.Material and methods. 10663 case histories of patients hospitalized for 5 years (2014-2018) were...

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Home blood pressure monitoring (HBPM) is strongly recommended by current guidelines as an effective out-of-office diagnostic and monitoring tool in patients with hypertension (HTN). However, there are personal, cultural, logistic difficulties owing to low effectiveness of HBPM. These put HBPM at a d...

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Abstract. Mediators of inflammation may play a sufficient role in destabilization of atherosclerotic plaque, disturbing the balance between collagen formation and its degradation in fibrotic capsule. Using a transgenic murine model, the effects of induced inflammation upon expression of factors dete...

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According to modern healthcare requirements, it is necessary to increase workforce capacity of primary care practice, therefore, improving the specialist training is one of the high-priority problems of medical education. Not enough attention is paid to paramedic education and their role in Russian...

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