Search Results - E. S. Filatova

The article presents a review of the epidemiology, etiology and pathogenesis of the carpal tunnel syndrome in various rheumatic diseases: rheumatoid arthritis, gout, systemic scleroderma, polymyalgia rheumatica. We also present our own data showing the prevalence of median nerve lesions in patients...

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Fibromyalgia (FM) affects 2 to 4 % of the population. In rheumatic diseases (RD), the frequency of FM is higher than in the general population, but the question remains whether it is a secondary disease, a complication of RD or an independent comorbid disorder.Objective: to determine whether FM in p...

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Objective: to study the contribution of neurogenic mechanisms to the pathogenesis of chronic pain in patients with rheumatoid arthritis (RA), knee osteoarthritis (OAk) and ankylosing spondylitis (AS). To evaluate the effectiveness of an anticonvulsants in complex therapy of RA and OAk.Patients and m...

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Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) contain a relatively low dose of their active ingredient and are intended for short-term use (for 3–5 days). They are effective and convenient in the treatment of musculoskeletal pain in many clinical situations in rheumatology practice....

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Objective: to reveal neurogenic mechanisms in the pathogenesis of chronic pain syndrome in rheumatoid arthritis (RA) and knee osteoarthritis (OA) in order to develop individualized pharmacotherapy.Subjects and methods. One hundred and eighty-three patients with RA and 80 with knee OA were examined....

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Purpose. Evaluati on of the effectiveness of complex restorati ve treatment with the inclusion of galvanic mud procedures in patients with pain in the lower back.Patients and methods. There were 30 patients (18 men and 12 women) with a diagnosis: lumbulgia or lumboeishalgia under observation. Patient...

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In the previous work, G.M. Sternik and S.G. Sternik justified the options for the method of assessing the average current annual return on investment in residential real estate development, depending on the nature and content of the initial data on the costs contained in the sources of information (...

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The market of container transportation is actively developing due to the universality of containers. It opens wide opportunities for transportation of absolutely any type of cargo, regardless of their volume, size and chemical condition. At the same time, the negative consequence of the use of this...

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The purpose of the study was to evaluate the clinical manifestations of osteoarthritis (OA) in combination with MS (OAMS) and their relationship with concentration of several circulating proinflammatory cytokines, the level of lipids in peripheral blood serum. Forty women patients with knee OA were...

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Background. Patients with the chronic migraine frequently present with memory and attention complaints. However, the prevalence and phenotype of such impairment in chronic migraine have not been studied.Objective – to evaluate the prevalence of the objective cognitive deficit in patients with chroni...

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The main symptom of osteoarthritis (OA) is pain. Mechanisms of chronic pain in OA have not been fully investigated yet.Objective: to study key mechanisms of chronic pain in patients with knee OA.Subjects and methods. Authors examined 80 women aged 45–65 years, with chronic pain due to OA of the knee...

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Over a half of chronic pain (CP) patients present with cognitive complaints, which increase their disability and impact quality of life. The paper reviews objective impairments in memory, attention, processing speed and executive function demonstrated in the CP population. The paper also reviews com...

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Background. Memory and attention deficits are prevalent in the chronic pain population. There are multiple common mechanisms in chronic pain and cognitive impairment. However, the presence, prevalence and clinical burden of such impairment are frequently underestimated.Objective: to evaluate subject...

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The literature review presents the current idea about the mechanisms of chronic pain. Experimental and clinical studies of the mechanism of chronic pain in osteoarthrosis (OA), which show that dysfunction of pain systems themselves (the so-called dysfunctional pain) along with the nociceptive mechan...

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The prevalence of fibromyalgia (FM) in the general population is 2–8%, and among patients with rheumatic diseases it is 2–3 times higher. The presence of comorbid FM significantly affects the course of rheumatoid arthritis (RA).Objective: to assess the effect of FM on RA activity indicators, feature...

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Pain control is the most important task in the complex treatment of osteoarthritis (OA). One of the promising methods to increase the efficacy of analgesics in OA may be the combined use of nonsteroidal antiinflammatory drugs (NSAIDs) with a complex of vitamins B1, B6 and B12 (СVB).Objective: to eva...

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Along with tissue damage, inflammation, and degenerative processes, central sensitization (spinal and supraspinal neuronal hyperactivity resulting from continuous nociceptive stimulation) plays an important role in the pathogenesis of chronic pain in rheumatic diseases (RDs). Functional magnetic res...

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Treatment of osteoarthritis (OA) patients with comorbidities can be challenging due to adverse events and non-sufficient efficacy of modern drugs. A safe and effective alternative could be the methods of traditional medicine and their combinations. The aim of this study was to evaluate efficacy and...

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The purpose of the study was to assess the effectiveness of the removal of nucleic acids (NA), Hepatitis B (HBV) and C (HCV) viruses and parvovirus B19 (B19V) from blood plasma fractions obtained by alcohol separation. The studies were performed in a model experiment by fractionation normal pool pla...

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Objective: to study the effect of neuropathic pain symptoms (SNP) on the clinical manifestations of rheumatoid arthritis (RA) in patients with moderate or high disease activity.Patients and methods. The 1st (main) group included 58 RA patients (84.5% of women, age 53.0±11.9 years), in whom SNP were...

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