Search Results - E. N. Bessonova

Aim of investigation. To study efficacy and complications of antiviral therapy in patients with liver cirrhosis of HCV-etiology.Material and methods. Original study included 57 patients with liver cirrhosis of HCV-etiology of A and B classes by Child-Pugh, treated in Sverdlovsk regional center of he...

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Aim of investigation. To study the urinary infection rate in patients with liver cirrhosis (LC) and indications for liver transplantation with assessment of etiologic spectrum and features of the progression of liver disease at development of this complication. Material and methods. The study includ...

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Introduction. One of the urgent tasks in modern transplantology is the search of biomarkers for predicting and early diagnosis of graft dysfunction.Objective. The study objective was to determine the biomarkers of liver graft dysfunction.Material and methods. We have examined 19 recipients who under...

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Aim: to determine the frequency of PNPLA3 rs738409 C>G gene polymorphism, leading to p.I148M substitution, in patients with non-alcoholic fatty liver disease (NAFLD), and to reveal the association between polymorphism and probable NAFLD outcomes: liver cirrhosis (LC) and hepatocellular carcin...

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Gaining the experience of liver transplantation waiting list formation is the important condition of transplant cen- ter successful work. In the era of transplant organ shortage careful medical examination of the patient before the operation and detection of unfavorable facts and transplantation con...

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Rationale. Portal blood flow is a key component in the viability of the liver transplant.Portocaval shunts formed on the background of the liver cirrhosis before transplantation can cause portal vein steal syndrome, with subsequent development of ischemic necrosis of the graft.To date, the tactics o...

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Introduction. In cirrhotic patients, hyperammonemia develops due to impaired ammonia detoxification and portosystemic blood shunting and is most commonly associated with hepatic encephalopathy and sarcopenia. Currently, there are questions regarding the diagnosis of hyperammonemia and the effect of...

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Аim: to describe modern approaches for screening and early diagnosis of hepatocellular carcinoma (HCC).Key points. Screening for HCC in high-risk groups (cirrhosis of any etiology, patients with chronic viral hepatitis B and patients with F3 liver fibrosis) should be organized as regular (every 6 mo...

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Today orthotopic liver transplantation is the only radical treatment of patients with end- stage chronic diffuse liver diseases. In Russia, liver transplantation is currently made in 8 transplantation centers of Moscow, Saint Petersburg, Yekaterinburg, Belgorod, Nizhni Novgorod, and Samara. The pape...

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Introduction. As a result of portal hypertension (sequestration of platelets in an enlarged spleen) and liver failure (decreased production of thrombopoietin in the liver) in liver cirrhosis, thrombocytopenia develops, which is associated with the risk of periprocedural/perioperative bleeding compli...

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