Kết quả tìm kiếm - E. L. Choinzonov

The article presents a biographical sketch of B.N. Zyryanov, a prominent Russian oncologist, Director of Tomsk Cancer Research Institute in the period from 1987 to 2002, Academician of the Russian Academy of Medical Sciences, Professor.

Twenty-five years have passed since the death of Nikolai Vladimirovich Vasiliev (1930–2001), the famous Russian scientist, philosopher and thinker, but the fruits of his foresight continue to surprise and amaze with their accuracy and insight. This article is devoted to a brief analysis of the situa...

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Abstract. We have studied possible interrelationships between immune system state and efficiency of neoadjuvant chemoradiotherapy in patients with cancer of larynx and hypopharynx. The neoadjuvant treatment consisted of 2 courses of paclitaxel (175 mg/m2), carboplatin (AUC-6 in 3-4 weeks), followed...

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Background. Distant organ tumor dissemination is a major cause of breast cancer-related deaths. Breast cancer can metastasize to several organs, and the most frequent metastatic sites include the bones, lungs and liver. There is a question what factors can influence the direction of spread of tumor...

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The purpose of the study was to determine the informative value of р53, CD 138 and Кi 67 markers in mucosal stratified squamous epithelium of patients with precancerous laryngeal lesions and laryngeal cancer. Material and methods. Expression of the above markers was analyzed in 80 patients with chro...

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Squamous cell carcinoma of head and neck (SCCHN) is often asymptomatic until it reaches the advanced stage. Currently, there are no available markers that can accurately predict the risk of progression of epithelial dysplasia to squamous cell carcinoma. The purpose of the study was to evaluate the f...

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Tomsk region refers to the areas of increased risk of malignancies, including laryngeal and upper respiratory tract cancers, which account for 2.0 % of all cancer cases. Approximately 83 new cancer cases (70 % in males) are annually diagnosed, with a tendency to increase. In 2014, the standardized i...

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High aggressiveness of laryngeal and hypopharyngeal squamous cell carcinomas dictates the necessity of studying the molecular mechanisms of metastasis. Cancer metastasis is associated with remodeling of the cytoskeleton, which is carried out by actin-binding proteins (ABPs). Currently, there is insu...

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We compared the serum proteome profiles of squamous cell head and neck carcinoma patients with metastases, without metastases and healthy volunteers using the combination of gradient gel-electrophoresis (1D-SDS PAGE) and mass-spectrometry. The study showed the difference in the serum proteome betwee...

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The review presents the diagnostic value of magnetic resonance imaging (MRI) in the diagnosis of soft tissue sarcoma in the pre-hospital period and during combined modality treatment was studied. Findings of using MRI in the assessment of local tumor extent and diffusion-weighted MRI and dynamic con...

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Findings of dynamic contrast-enhanced magnetic resonance imaging with the use of the time-signal intensity curve were assessed in patient with thyroid cancer. Diagnostic value of high-field dynamic contrast-enhanced MRI in detection of thyroid cancer was analyzed.

The review deals with the problem of comprehensive diagnostic capabilities for thyroid cancer. In spite of the multiple studies, the question on the role of magnetic-resonance imaging in diagnostic algorithms for thyroid cancer remains disputable

Background. The non-declining cervical cancer incidence in the Siberian Federal District 16.30/0000 (in Russia - 13.80 /0000) necessitate preventive vaccination against the human papillomavirus (HPV).Aim. To evaluate the cost-effectiveness of HPV vaccination in girls aged 9-14 years in the Siberian...

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The results of the combined modality treatment including neutron therapy for patients with resistant malignant tumors were presented. Efficacy of neutron therapy was assessed using disease-free and 5-year survival rates. Neutron therapy used alone or as a combination therapy was shown to be more eff...

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The aim of the study was to evaluate the high-field magnetic resonance imaging (MRI) findings in patients with nodular lesions of the thyroid before surgery. The study included 33 patients with benign lesions and 18 patients with histologically-verified thyroid cancer.The diagnostic value of high-fi...

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The purpose of the study was a systematic literature review of imaging assessment of lymph node metastasis in patients with laryngeal and hypopharyngeal cancer.Material and methods. In order to review the most relevant scientific literature available, we searched Elibrary, Medline databases (from Ja...

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Laryngeal and hypopharyngeal cancer takes the leading position among malignant head and neck tumors, representing one of the most important and socially significant problems in modern oncology. Approaches to the treatment of locally advanced laryngeal or hypopharyngeal cancer have changed significan...

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We performed the analysis of the markets and sectors of the economy, the development of which is ensured by the implementation of the priority 20v «the transition to personalized medicine, high-tech health care and health protection technologies» in the field of post-genomic technologies, including...

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MicroRNA are nonprotein-coding small ribonucleic acids controlling gene expression at post-transcriptional level. MicroRNA technically could controll 2/3 of human genome. At the present study abnormal expression of microRNA-18а, -21, -155, -200а, -200с, -205, -221, -494 in malignant tissue of squamo...

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