Search Results - E. G. Pukhaeva

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  1. 1
    Metabolic changes of lymphocytes in a rat model of autoimmunity

    Metabolic changes of lymphocytes in a rat model of autoimmunity by S. V. Skupnevsky, E. G. Pukhaeva, A. K. Badtiev, F. K. Rurua, F. E. Batagova, Z. G. Farnieva

    Published 2022-04-01

    Autoimmune diseases are highly prevalent in humans, being characterized by early onset and high risks of disability, thus determining the relevance of the present work and its aim, i.e., studying metabolic characteristics of lymphocytes upon the adjuvant-induced autoimmune disorder in rats. Modeling...

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  2. 2
    The role of the metabolic status of lymphocytes in the pathogenesis of rheumatoid arthritis

    The role of the metabolic status of lymphocytes in the pathogenesis of rheumatoid arthritis by S. V. Skupnevsky, E. G. Pukhaeva, A. K. Badtiev, F. K. Rurua, F. E. Batagova, Zh. G. Farnieva

    Published 2021-10-01

    Objective: to study in dynamics metabolic changes in lymphocytes on the model of adjuvant-induced rheumatoid arthritis (RA) in warm-blooded animals.Material and methods. The RA model was elicited by administering Freund's complete adjuvant (AF) to male Wistar rats. Lymphocyte metabolism was cor...

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  3. 3
    Mononuclear cells from human umbilical cord/placental blood: Assessment of allergenicity and impact on immune status in experimental warm-blooded animals

    Mononuclear cells from human umbilical cord/placental blood: Assessment of allergenicity and impact on immune status in experimental warm-blooded animals by S. V. Skupnevskiy, R. V. Saveljev, E. G. Pukhaeva, Ya. V. Morozova, S. M. Radaev, V. A. Smirnov, A. A. Grin

    Published 2025-03-01

    Human mononuclear cells from umbilical cord blood (HUCBMCs) are used as the main or adjuvant therapy for treatment of about 80 different diseases, due to high proliferative activity of these cells, low immunogenicity and an opportunity of selecting rare HLA types for transplants. In this regard, ass...

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