Søgeresultater - Douglas F Easton

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  1. 1
    Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

    Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. af Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

    Udgivet 2014-01-01

    <h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. The role of TLR4 in the pathophysiology of several ag...

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  2. 2
    GWAS meta-analysis identifies five susceptibility loci for endometrial cancerResearch in context

    GWAS meta-analysis identifies five susceptibility loci for endometrial cancerResearch in context af Dhanya Ramachandran, Xuemin Wang, Triin Laisk, Ying Zheng, Nathan Ingold, Daffodil M. Canson, Pik Fang Kho, Bianca J. Naumann, Carly J. Chapman, Kristine Bousset, Anna V. Krause, Peter Schürmann, Britta Wieland, Patricia Hanel, Fabienne Hülse, Norman Häfner, Ingo Runnebaum, Natalia Dubrowinskaja, Nurzhan Turmanov, Tatyana Yugay, Zura Berkutovna Yessimsiitova, Frédéric Amant, Daniela Annibali, Matthias W. Beckmann, Clara Bodelon, Daniel D. Buchanan, Chu Chen, Megan A. Clarke, Linda S. Cook, Immaculata De Vivo, Wout De Wispelaere, Mengmeng Du, Douglas F. Easton, Julius Emons, Peter A. Fasching, Christine M. Friedenreich, Grace Gallagher, Graham G. Giles, Ellen L. Goode, Holly R. Harris, David J. Hunter, David L. Kolin, Peter Kraft, James V. Lacey, Diether Lambrechts, Lingeng Lu, George L. Mutter, Jeffin Naduparambil, Kelli O’Connell, Alpa V. Patel, Paul D.P. Pharoah, Timothy R. Rebbeck, Fulvio Ricceri, Harvey A. Risch, Matthias Ruebner, Carlotta Sacerdote, Rodney J. Scott, V. Wendy Setiawan, Xiao-Ou Shu, Melissa C. Southey, Emma Tham, Ian Tomlinson, Constance Turman, Nicolas Wentzensen, Wanghong Xu, Herbert Yu, Wei Zheng, Amanda B. Spurdle, Yosef Yarden, Reedik Mägi, Peter Hillemanns, Dylan M. Glubb, Thilo Dörk, Tracy A. O’Mara

    Udgivet 2025-08-01

    Summary: Background: Endometrial cancer is the most common gynaecological cancer in high-income countries. In addition to environmental risk factors, genetic predisposition contributes towards endometrial cancer development but is still incompletely defined. Methods: Building on genome-wide associa...

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  3. 3
    Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.

    Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. af Madalene Earp, Jonathan P Tyrer, Stacey J Winham, Hui-Yi Lin, Ganna Chornokur, Joe Dennis, Katja K H Aben, Hoda Anton-Culver, Natalia Antonenkova, Elisa V Bandera, Yukie T Bean, Matthias W Beckmann, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Clareann H Bunker, Ralf Butzow, Ian G Campbell, Karen Carty, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Julie M Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Douglas F Easton, Diana M Eccles, Robert P Edwards, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Aleksandra Gentry-Maharaj, Graham G Giles, Rosalind Glasspool, Marc T Goodman, Jacek Gronwald, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A T Hildebrandt, Peter Hillemanns, Claus K Hogdall, Estrid Høgdall, Satoyo Hosono, Edwin S Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Audrey Y Jung, Beth Y Karlan, Melissa Kellar, Lambertus A Kiemeney, Boon Kiong Lim, Susanne K Kjaer, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D Le, Shashi Lele, Jenny Lester, Douglas A Levine, Zheng Li, Dong Liang, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F A G Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Iain McNeish, Usha Menon, Roger L Milne, Francesmary Modugno, Kirsten B Moysich, Roberta B Ness, Heli Nevanlinna, Kunle Odunsi, Sara H Olson, Irene Orlow, Sandra Orsulic, James Paul, Tanja Pejovic, Liisa M Pelttari, Jenny B Permuth, Malcolm C Pike, Elizabeth M Poole, Barry Rosen, Mary Anne Rossing, Joseph H Rothstein, Ingo B Runnebaum, Iwona K Rzepecka, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C Southey, Beata Spiewankiewicz, Lara Sucheston-Campbell, Ingvild L Tangen, Soo-Hwang Teo, Kathryn L Terry, Pamela J Thompson, Lotte Thomsen, Shelley S Tworoger, Anne M van Altena, Ignace Vergote, Liv Cecilie Vestrheim Thomsen, Robert A Vierkant, Christine S Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S Whittemore, Kristine G Wicklund, Lynne R Wilkens, Yin-Ling Woo, Anna H Wu, Xifeng Wu, Yong-Bing Xiang, Hannah Yang, Wei Zheng, Argyrios Ziogas, Alice W Lee, Celeste L Pearce, Andrew Berchuck, Joellen M Schildkraut, Susan J Ramus, Alvaro N A Monteiro, Steven A Narod, Thomas A Sellers, Simon A Gayther, Linda E Kelemen, Georgia Chenevix-Trench, Harvey A Risch, Paul D P Pharoah, Ellen L Goode, Catherine M Phelan

    Udgivet 2018-01-01

    Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality in American women. Normal ovarian physiology is intricately connected to small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and Ran) which govern processes such as signal transduction, cell proliferati...

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