Search Results - Deng-ke PAN

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  1. 1
    Highly efficient generation of GGTA1 knockout pigs using a combination of TALEN mRNA and magnetic beads with somatic cell nuclear transfer

    Highly efficient generation of GGTA1 knockout pigs using a combination of TALEN mRNA and magnetic beads with somatic cell nuclear transfer by Chong FENG, Xi-rui LI, Hui-ting CUI, Chuan LONG, Xia LIU, Xing-hua TIAN, Deng-ke PAN, Yu-zhu LUO

    Published 2016-07-01

    The transcription activator-like effector nuclease (TALEN) technique combined with the somatic cell nuclear transfer (SCNT) method has been successfully applied for creating genetically modified pigs. However, methods for isolating cells with biallelic indels requires further improvement because of...

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  2. 2
    Transcriptomic analysis elucidates the enhanced skeletal muscle mass, reduced fat accumulation, and metabolically benign liver in human follistatin-344 transgenic pigs

    Transcriptomic analysis elucidates the enhanced skeletal muscle mass, reduced fat accumulation, and metabolically benign liver in human follistatin-344 transgenic pigs by Ke-ren LONG, Xiao-kai LI, Ruo-wei ZHANG, Yi-ren GU, Min-jie DU, Xiang-yang XING, Jia-xiang DU, Miao-miao MAI, Jing WANG, Long JIN, Qian-zi TANG, Si-lu HU, Ji-deng MA, Xun WANG, Deng-ke PAN, Ming-zhou LI

    Published 2022-01-01

    Follistatin (FST) is an important regulator of skeletal muscle growth and adipose deposition through its ability to bind to several members of the transforming growth factor-β (TGF-β) superfamily, and thus may be a good candidate for future animal breeding programs. However, the molecular mechanisms...

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