Search Results - Deborah J Cook

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  1. 1
    Pressure and volume limited ventilation for the ventilatory management of patients with acute lung injury: a systematic review and meta-analysis.

    Pressure and volume limited ventilation for the ventilatory management of patients with acute lung injury: a systematic review and meta-analysis. by Karen E A Burns, Neill K J Adhikari, Arthur S Slutsky, Gordon H Guyatt, Jesus Villar, Haibo Zhang, Qi Zhou, Deborah J Cook, Thomas E Stewart, Maureen O Meade

    Published 2011-01-01

    <h4>Background</h4>Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life threatening clinical conditions seen in critically ill patients with diverse underlying illnesses. Lung injury may be perpetuated by ventilation strategies that do not limit lung volumes an...

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  2. 2
    Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol

    Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol by Sangeeta Mehta, Deborah J Cook, Kimberley Lewis, Roman Jaeschke, Dan Perri, Corry Marchildon, Kelly Hassall, Thomas Piraino, Waleed Alhazzani, Erick Huaileigh Duan, Karen Bosma, Jose Estrada, Irene Armanious, Kallirroi Laiya Carayannopoulos

    Published 2025-06-01

    Introduction The cuff leak test (CLT) is hypothesised to help optimise extubation by assessing for laryngeal oedema which, if unrecognised and untreated, could lead to post-extubation stridor, post-extubation airway obstruction, and reintubation. However, the diagnostic accuracy of the CLT to detect...

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