Search Results - De Chang

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    Effects of non-HDL-C and statin therapy on mortality in ARDS: a retrospective cohort study by Haiming Hu, Haiming Hu, Haiming Hu, Jin Wei, Lijuan Zhao, Lijuan Zhao, Yixing Zhu, Yixing Zhu, Yixing Zhu, Geer Zhou, Geer Zhou, Geer Zhou, Anqi Zhao, Anqi Zhao, Anqi Zhao, De Chang, De Chang

    Published 2025-07-01

    BackgroundAcute respiratory distress syndrome (ARDS) is a critical and potentially fatal condition marked by inflammation and coagulation disorders. Statins, a class of cholesterol-lowering medications, have been explored for potential anti-inflammatory properties, yet their exact role in ARDS remai...

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    Significant Reduction of Chenodeoxycholic Acid and Glycochenodeoxycholic Acid in the Elderly with Severe COVID-19 by Shiyang Liu, Wen Xu, Bo Tu, Zhiqing Xiao, Xue Li, Lei Huang, Xin Yuan, Shengdong Luo, Juanjuan Zhou, Xinxin Yang, Junlian Yang, De Chang, Weiwei Chen, Fu-Sheng Wang

    Published 2025-06-01

    Elderly individuals infected with SARS-CoV-2 are at higher risk of developing cytokine storms and severe outcomes, yet specific biomarkers remain unclear. In this study, we investigated the alteration of primary bile acid metabolism in elderly patients with severe COVID-19 using untargeted metabolom...

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