Torthaí cuardaigh - Danielle Sullivan

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    Safety and pharmacokinetics of veliparib extended‐release in patients with advanced solid tumors: a phase I study

    Safety and pharmacokinetics of veliparib extended‐release in patients with advanced solid tumors: a phase I study de réir Theresa L. Werner, Jasgit Sachdev, Elizabeth M. Swisher, Martin Gutierrez, Muaiad Kittaneh, Mark N. Stein, Hao Xiong, Martin Dunbar, Danielle Sullivan, Philip Komarnitsky, Mark McKee, Antoinette R. Tan

    Foilsithe / Cruthaithe 2018-06-01

    Abstract The poly(ADP‐ribose) polymerase‐1/2 inhibitor veliparib is active against tumors deficient in homologous DNA damage repair. The pharmacokinetics and safety of veliparib extended‐release (ER) were evaluated in patients with advanced solid tumors. This phase I study assessed veliparib‐ER up t...

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