Risultati della ricerca - Dan Zhou

Klinefelter syndrome (KS; 47,XXY) is the most common sex chromosome disorder, affecting approximately 1 in every 500 to 650 newborn males. Children with KS display a spectrum of phenotypic manifestations, including abnormal neurocognitive phenotypes. However, due to the limited research focusing on...

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CXC chemokine receptor 3 (CXCR3) is a G protein-coupled chemokine receptor that plays a key role in regulating immune responses and is involved in various pathological processes, particularly in tumor development and inflammatory diseases, making it a novel target for clinical therapy. The expressio...

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There is increasing demand for the traditional Chinese medicine Hedyotis diffusa Willd. due to its effectiveness in treating hepatitis and malignant tumors of the liver, lung, and stomach. Hedyotis corymbosa (L.) Lam. has commonly become an adulterant of H. diffusa Willd. The proofreading enzyme-med...

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ObjectiveThis study aims to develop and validate a model based on clinical and radiomic features to investigate its value in distinguishing between benign and malignant breast nodules.MethodsThe study included 139 patients with breast diseases, divided into a training set (n=111) and a validation se...

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BackgroundThe rising global burden of invasive fungal infections and the growing issue of antifungal resistance present critical public health threats. By using multicenter surveillance data from Sichuan Province, we conducted the largest five-year study on fungemia to date. Our objective was to gai...

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BackgroundPrevious studies have demonstrated that ozone injection into the dorsal root ganglion significantly reduces pain scores associated with herpes zoster, suggesting its therapeutic potential for managing postherpetic neuralgia (PHN) via the intervertebral foramen epidu...

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With the rapid advancement of satellite remote sensing technology, high-resolution optical remote sensing images have become increasingly crucial for monitoring energy infrastructure. Traditional change detection methods identify land-use and land cover variations over time, while image retrieval ex...

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Protein phosphorylation plays a critical role during the development of malaria parasites. Here, we performed a functional analysis of the Plasmodium berghei Ser/Thr protein phosphatase 6 (PbPP6), which is associated with the plasma membrane of macrogametes and ookinetes. Compared to wild-type P. be...

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Chemotherapy is currently the mainstay of systemic management for triple-negative breast cancer (TNBC), but chemoresistance significantly impacts patient outcomes. Our research indicates that Doxorubicin (Dox)-resistant TNBC cells exhibit increased glycolysis and ATP generation compared to their par...

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AimsTo explore the clinicopathological features and renal outcome in patients with cryoglobulinemic glomerulonephritis (Cryo-GN) without confirmed systemic autoimmune diseases.MethodsSixty-nine patients with Cryo-GN from a single center were recruited in this retrospective study. Their clinical, pat...

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